检验医学与临床2024，Vol.21Issue(1)：118-122,5.DOI:10.3969/j.issn.1672-9455.2024.01.027
腹腔镜下根治性顺行模块化胰脾切除术与脻体尾切除术治疗胰体尾癌的效果分析
Analysis on efficacy of laparoscopic radical anterograde modular pancreaticosplenectomy and distal pancreaticosplenectomy in treatment of pancreatic body and tail cancer
王涛 1常莹 1王钢 1李永利 1雷达1
作者信息
- 1. 陕西省宝鸡市中心医院肝胆胰脾外科二科,陕西宝鸡 721008
- 折叠
摘要
Abstract
Objective To analyze the efficacy of laparoscopic radical anterograde modular pancreaticosple-nectomy(LRAMPS)and distal pancreaticosplenectomy(DPS)in the treatment of pancreatic body and tail cancer.Methods The clinical data in 68 cases of pancreatic body and tail cancer treated in this hospital from June 2018 to June 2022 were selected.The patients were divided into the LRAMPS group(40 cases)and the DPS group(46 cases)according to the different surgical methods chosen by the patients.The surgical situa-tion and postoperative prognosis etc.were compared between the two groups.Two groups were followed up until December 2022.The survival situation in the two groups was analyzed.Results The both groups suc-cessfully completed the surgery without the death during hospitalization.The intraoperative bleeding volume of the LRAMPS group was lower than that of the DPS group(P＜0.05),the visual analogue scale(VAS)scores at postoperative 24 h in the LRAMPS group was lower than that in the DPS group(P＜0.05),and the R0 incision rate in the LRAMPS group was higher than that in the DPS group(P＜0.05).There was no statis-tically significant difference in the total treatment effect rate between the two groups(P＞0.05).The two groups were followed up for 6-54 months,the recurrence rate and liver metastasis rate in the LRAMPS group were significantly lower than those in the DPS group(P＜0.05).The postoperative median survival time in the LRAMPS group was 18.5 months and 12.2 months in the DPS group,and the difference was sta-tistically significant(P＜0.05).The survival rates in postoperative 18,24,36,48,54 months in the LRAMPS group were significantly higher than those in the DPS group(P＜0.05).Conclusion There are no significant difference in the short-term prognosis between the DPS surgery and LRAMPS group for treating pancreatic body and tail cancer,but LRAMPS could reduce the intraoperative bleeding volume and postoperative pain of the patients.In terms of longer prognosis,LRAMPS has a better therapeutic effect than DPS,which could ef-fectively prolong the patient's survival period,increase the patient's survival rate and improve the patient's prognosis.关键词
腹腔镜/根治性顺行模块化胰脾切除术/脻体尾切除术/胰体尾癌/疗效Key words
laparoscope/radical antegrade modular pancreaticosplenectomy/distal pancreaticosplenec-tomy/pancreatic body and tail cancer/efficacy分类
医药卫生引用本文复制引用
王涛,常莹,王钢,李永利,雷达..腹腔镜下根治性顺行模块化胰脾切除术与脻体尾切除术治疗胰体尾癌的效果分析[J].检验医学与临床,2024,21(1):118-122,5.
