临床小儿外科杂志2023，Vol.22Issue(12)：1146-1150,5.DOI:10.3760/cma.j.cn101785-202209023-010
儿童超短肠综合征治疗分析
Managements of ultra-short bowel syndrome in infants
摘要
Abstract
Objective To explore the treatments and outcomes of infants with ultra-short bowel syn-drome(USBS).Methods From January 2015 to February 2021,retrospective review was conducted for 24 USBS infants.Clinical characteristics,treatments and outcomes were recorded.There were 17 boys and 7 girls with a gestational age of(26-39+5)week and a range of birth weight(720-3 600)gram.The infants were premature(n=20)and full-term(n=4).Results Among them,7 infants of temporary USBS were dis-charged upon completing short-term nutritional therapy after closing stoma;7/17 infants of non-temporary USBS were weaned off parenteral nutrition to achieve intestinal adaptation;5/17 relinquished further treatments dur-ing operation;5/17 required continued parenteral nutrition.Among 19 survivors,there were intravenous nutri-tion-related cholestasis(n=9),catheter infection(n=9),acquired zinc deficiency dermatitis(n=3),vitamin D deficiency(n=6)and metabolic bone disease(n=2).All symptoms improved after symptomatic measures.Conclusions It is rather troublesome to manage USBS children and there are numerous complications.After proper treatments,some infants may finally achieve intestinal adaptation without parenteral nutrition关键词
短肠综合征/超短肠综合征/肠道营养/胃肠外营养/手术后并发症/治疗/预后/儿童Key words
Short Bowel Syndrome/Ultra-short Bowel Syndrome/Enteral Nutrition/Parenteral Nutri-tion/Postoperative Complications/Therapy/Prognosis/Child引用本文复制引用
赵晓霞,韩一江,吕成杰,黄寿奖,钭金法,汪家莉,胡书奇,高佳芳,秦琪,赖登明,马东,陈锐,王鹏..儿童超短肠综合征治疗分析[J].临床小儿外科杂志,2023,22(12):1146-1150,5.基金项目
浙江省自然科学基金(LY21H150005)Zhejiang Provincial Natural Science Foundation of China(LY21H150005) （LY21H150005）
