水产学报2024，Vol.48Issue(1)：1-16,16.DOI:10.11964/jfc.20230213903
硬骨鱼类虹彩细胞的研究进展
Research advances of iridophores in Teleosts
摘要
Abstract
The iridophore is a kind of common pigment cell in teleosts.It contains a large number of iridosomes,which contain reflecting platelets with high refractive index composed of guanine crystals.The reflecting platelets and the cytoplasm with low refractive index are alternately arranged to form alternating layers.After light is reflec-ted by the alternating layers,the iridophores show an iridescent color through multilayer thin-film interference.Iridophores achieve color change by changing the distances between each of the reflecting platelets under the stim-ulation of hormones,sympathetic nervous system or external environment factors.Guanine is the basis for the col-oration and color changes of iridophores,and its biosynthesis pathway has been analyzed in detail.Iridophores are differentiated from multipotent neural crest cells.The lineage specialization process of differentiation from neural crest cells to mature iridophores requires multiple genes.At present,some key genes have been found in the model organism,zebrafish,and the core gene regulatory network governing iridophore specification has been preliminar-ily analyzed through studying the interactions among those genes.At the same time,other genes and signaling pathways affecting the specialization,differentiation and survival of iridophores have also been found.This manuscript reviews advances of studies in the mechanism of coloration and color change of iridophores,the path-way and genes involved in guanine biosynthesis,as well as genes and signaling pathways affecting the develop-ment and survival of iridophores in teleosts.Prospects for future research directions are also provided.It is aimed at a deeper understanding of iridophores and providing a reference for studying gene regulation during iridophore development.关键词
硬骨鱼类/模式鱼类/虹彩细胞/鸟嘌呤合成/颜色变化/谱系特化/基因调控/信号通路Key words
Teleosts/model fishes/iridophore/guanine biosynthesis/color change/lineage specification/gene regulation/signaling pathway分类
农业科技引用本文复制引用
田浚杉,唐雨馨,王晨旭,王德寿..硬骨鱼类虹彩细胞的研究进展[J].水产学报,2024,48(1):1-16,16.基金项目
国家自然科学基金(31872556,31861123001) （31872556,31861123001）
重庆市水产科技创新联盟项目(2023) （2023）
国家级大学生创新创业训练计划项目(202210635098) National Natural Science Foundation of China(31872556,31861123001) （202210635098）
Chongqing Fishery Technology Innovation Union(2023) （2023）
National Training Program of Innovation and Entrepreneurship for Under-graduates(202210635098) （202210635098）
