摘要
Abstract
Objective:To investigate the effectiveness of the intrauterine contraceptive devices,COOK balloon stents,and cross-linked sodium hyaluronate gel in treating readhesions after moderate and severe intrauterine adhesion dissociation.Methods:A total of 128 patients with moderate to severe uterine adhesions,who underwent hysteroscopic separation of uterine adhesions at the Gynecology Inpatient Department of Puning Maternal and Child Health and Family Planning Service Center from January 2014 to January 2019,were selected.The patients were divided into six groups.All patients in the six groups received estradiol valerate therapy after transcervical resection of adhesion to repair the endometrium and underwent follow-up.At the third month after treatment,the recovery of menstruation was observed,and hysteroscopy was performed to evaluate the treatment effectiveness of the six groups.Pregnancy status was observed and followed up in the six groups from the third month to one year after surgery.Results:The effective rates of preventing moderate intrauterine adhesion recurrence were 63.64%,77.27%,and 72.73%.The pregnancy rates were 63.64%,40.91%,and 45.45%.No significant difference was found in the effective rate and pregnancy rate among the three groups(P>0.05).The effective rates of preventing severe intrauterine adhesion recurrence were 23.81%,61.90%and 65.00%.The pregnancy rates were 4.76%,38.10%,and 35.00%.The effective rate and pregnancy rate of the severe intrauterine adhesions COOK balloon stent group and severe intrauterine adhesion intrauterine cross-linked sodium hyaluronate gel group were higher than those of the intrauterine contraceptive device group,the difference was statistically significant(P≤0.05).No significant difference was observed in the effective rate and pregnancy rate between the severe intrauterine adhesions COOK balloon stent group and the self-cross-linked sodium hyaluronate gel group(P>0.05).Conclusion:In patients with severe intrauterine adhesions after transcervical resection of adhesions,the implantation of COOK balloon stent or cross-linked sodium hyaluronate gel into the uterine cavity is beneficial in preventing the recurrence of adhesions.The treatment's effectiveness rate and pregnancy rate are better than that of intrauterine contraceptive devices.关键词
宫腔镜/宫腔粘连/宫腔粘连复发/对比研究Key words
hysteroscopy/intrauterine adhesions/recurrent uterine adhesions/comparative study分类
医药卫生
