生殖医学杂志2024,Vol.33Issue(1):122-128,7.DOI:10.3969/j.issn.1004-3845.2024.01.020
微生物感染在慢性子宫内膜炎致生殖障碍中的机制进展
Research progress on mechanism of reproductive disorders caused by microbial infections in chronic endometritis
摘要
Abstract
Chronic endometritis(CE)is mainly a chronic inflammatory disease of the endometrium caused by pathogenic microorganisms in the uterine cavity,which is closely related to female reproductive disorders,but its specific mechanism is not yet clear.In recent years,studies have suggested that the main reason why chronic endometritis affects female reproductive outcomes is not only the presence of uterine microorganisms,but also the interaction between the microbial community and the endometrial microecology,which is related to uterine dysbiosis,metabolic changes,endometrial immune inflammation disorders,and abnormal gene expression.This paper reviews the research progress on the mechanism of microbiota in the occurrence and development of CE,as well as its impact on female reproductive health.It helps to provide scientific basis for optimizing treatment plans and improving reproductive prognosis in clinical practice.关键词
慢性子宫内膜炎/病原微生物/生殖障碍Key words
Chronic endometritis/Pathogenic microorganisms/Reproductive disorders分类
医药卫生引用本文复制引用
王静怡,袁莹,邹志玲,陈雪梅..微生物感染在慢性子宫内膜炎致生殖障碍中的机制进展[J].生殖医学杂志,2024,33(1):122-128,7.基金项目
东莞市社会科技发展(重点)项目(201950715024177) (重点)