临床医学工程2024，Vol.31Issue(1)：37-38,2.DOI:10.3969/j.issn.1674-4659.2024.01.0037
阿托伐他汀钙联合苯磺酸氨氯地平治疗动脉粥样硬化的临床研究
Clinical Study on Atorvastatin Calcium Combined with Amlodipine Besylate in the Treatment of Atherosclerosis
摘要
Abstract
Objective To explore the clinical effect of atorvastatin calcium combined with amlodipine besylate in the treatment of atherosclerosis.Methods 74 patients with atherosclerosis admitted to our hospital from February 2020 to February 2023 were selected and randomly divided into control group(37 cases,amlodipine besylate)and observation group(37 cases,atorvastatin calcium combined with amlodipine besylate).The treatment effect,blood lipid level and lipoprotein-associated phospholipase A2(LP-PLA2)level were compared between the two groups.Results The total effective rate of treatment and HDL-C level in the observation group were significantly higher than those in the control group,and the TC,TG,LDL-C and LP-PLA2 levels were significantly lower than those in the control group(P<0.05).Conclusions Atorvastatin calcium combined with amlodipine besylate in the treatment of atherosclerosis has significant effect,and also has positive effect on the regulation of lipid metabolism and improvement of vascular inflammatory state in patients.关键词
阿托伐他汀钙/苯磺酸氨氯地平/动脉粥样硬化/治疗效果Key words
Atorvastatin calcium/Amlodipine besylate/Atherosclerosis/Treatment effect分类
医药卫生引用本文复制引用
陈君,尹俊锋,逄涛..阿托伐他汀钙联合苯磺酸氨氯地平治疗动脉粥样硬化的临床研究[J].临床医学工程,2024,31(1):37-38,2.基金项目
河南省医学科技攻关计划联合共建项目(2018020729) （2018020729）
