临床医学工程2024，Vol.31Issue(1)：45-46,2.DOI:10.3969/j.issn.1674-4659.2024.01.0045
沙库巴曲缬沙坦钠在急性心肌梗死介入术后的应用价值
Application Value of Sacubitril Valsartan Sodium in Patients after Acute Myocardial Infarction Intervention
摘要
Abstract
Objective To explore the application value of sacubitril valsartan sodium in patients after acute myocardial infarction(AMI)intervention.Methods 70 AMI patients admitted to our hospital from May 2022 to April 2023 were divided into two groups according to lottery method.The observation group was treated with sacubitril valsartan sodium,and the control group was treated with enalapril.The cardiac function,serum indicators and prognosis were compared between the two groups.Results After treatment,the LVESD and LVEDD of the two groups decreased,the LVEF increased(P<0.05);The LVESD and LVEDD of the observation group were lower than those of the control group,and the LVEF was higher than that of the control group(P<0.05).After treatment,the NT-proBNP and CK-MB levels of the two groups decreased,and the NT-proBNP and CK-MB levels of the observation group were lower than those of the control group(P<0.05).The incidence of MACE in observation group was 11.43%,lower than 31.43%in the control group(P<0.05).Conclusions Early application of sacubitril valsartan sodium can prevent myocardial remodeling after AMI intervention,protect the cardiac function and improve prognosis.关键词
沙库巴曲缬沙坦钠/急性心肌梗死/介入术Key words
Sacubitril valsartan sodium/Acute myocardial infarction/Percutaneous coronary intervention分类
医药卫生引用本文复制引用
宋晓雨,张铁锋..沙库巴曲缬沙坦钠在急性心肌梗死介入术后的应用价值[J].临床医学工程,2024,31(1):45-46,2.基金项目
河南省医学科技攻关计划联合共建项目(LHGJ20190919) （LHGJ20190919）
