中国临床药学杂志2023，Vol.32Issue(6)：412-417,6.DOI:10.19577/j.1007-4406.2023.06.003
基于Beers标准和STOPP/START标准评价高龄老年住院患者潜在不适当用药
Evaluation of the Beers and STOPP/START criterias for potentially inappropriate medications in older hospitalized patients
王研 1刘霞 1林艳 1余自成1
作者信息
- 1. 同济大学附属杨浦医院药学部,上海 200090
- 折叠
摘要
Abstract
AIM To investigate the potential inappropriate medication(PIM)and potential prescription omission(PPO)in ederly inpatients by using 2 different evaluation criterias,so as to provide reference for the standardization of clinical medication in older patients.METHODS The PIM and PPO status of inpatients(aged>80 years)discharged from department of geriatrics from January to December 2021 were analyzed based on Beers criteria(2019 edition)and STOPP/START criteria(2014 edition).RESULTS Among 124 patients,the Beers criteria identified 134 PIM in 85 patients(68.50％);20 patients(16.13％)had disease-related PIM,with a total of 22 occurrences.The STOPP/START criteria detected 54 PIM in 46 patients(37.10％);24 patients(19.35％)existed PPO,with a total of 32 occurrences.The results of both screening methods showed that the drugs involved in a higher frequency of PIM was benzodiazepines(BDZs).In disease-related PIM,36.36％of heart failure patients were treated with diltiazem,aspirin and cilostazol by Beers criteria.The PPO of diabetes patients with one or more major cardiovascular risk factors without receiving statin treatment accounted for 28.13％by START criteria.Logistic regression analysis indicated that the number of drug varieties was the risk factor for PIM.Beers criteria and STOPP/START criteria had poor consistency in results(Kappa=0.338,P＜0.001).CONCLUSION PIM and PPO in the treatment of ederly hospitalized patients should be taken seriously,and the management of pharmacotherapy also needs to be strengthened.The Beers criteria and STOPP/START criteria can complement each other to a certain extent,allowing for a more comprehensive screening of PIM and PPO.关键词
高龄老年患者/潜在不适当用药/Beers标准/STOPP/START标准Key words
elderly patient/potentially inappropriate medication/Beers Criteria/STOPP/START criteria引用本文复制引用
王研,刘霞,林艳,余自成..基于Beers标准和STOPP/START标准评价高龄老年住院患者潜在不适当用药[J].中国临床药学杂志,2023,32(6):412-417,6.
