中国医院用药评价与分析2023，Vol.23Issue(12)：1446-1449,4.DOI:10.14009/j.issn.1672-2124.2023.12.007
西医常规治疗联合芪蛭通络胶囊对急性缺血性脑卒中介入术后患者恢复的临床研究
Clinical Study on Patients'Recovery After Acute Ischemic Stroke Intervention by Conventional Western Medicine Combined with Qizhi Tongluo Capsules
摘要
Abstract
OBJECTIVE:To probe into the clinical effect of conventional Western medicine combined with Qizhi Tongluo capsules on patients'recovery after acute ischemic stroke intervention.METHODS:A total of 86 patients with acute ischemic stroke underwent interventional operation in the interventional medicine department of Xuzhou Cancer Hospital from Jun.2019 to Dec.2021 were selected and divided via the random number table method,43 cases in the control group were given aspirin and conventional rehabilitation treatment;43 cases in the observation group received Qizhi Tongluo capsules on the basis of the control group.After continuous treatment for 3 months,the clinical efficacy,degree of neurological impairment[National Institutes of Health Stroke Neurologic Deficit Scale(NIHSS)scores],hemorheological indicators(whole blood high shear viscosity,whole blood low shear viscosity and plasma viscosity level),quality of life score[activities of daily living(ADL)scores]and incidences of adverse drug reactions were compared between two groups.RESULTS:After 3 months of treatment,the total effective rate of the observation group was 93.0%(40/43),which was higher than that of the control group(76.7%,33/43),with statistically significant difference(P<0.05).The NIHSS scores of both groups decreased significantly after treatment compared with those before treatment,and the NIHSS scores in the observation group was lower than that in the control group,with statistically significant differences(P<0.05).The whole blood high shear viscosity,whole blood low shear viscosity and plasma viscosity levels of both groups decreased compared with those before treatment,and the above indicators in the observation group were lower than those in the control group,with statistically significant differences(P<0.05);the ADL scores of both groups increased compared with those before treatment,and the ADL scores in the observation group was higher than that in the control group,with statistically significant differences(P<0.05).The incidences of adverse drug reactions of the observation group was 7.0%(3/43),lower than that of the control group(18.6%,8/43),the difference was not statistically significant(P>0.05).CONCLUSIONS:The efficacy of conventional Western medicine combined with Qizhi Tongluo capsules in the treatment of patients with acute ischemic stroke after interventional surgery is remarkable,which can improve neurological function damage,regulate hemorheology,promote the quality of life,with high safety.关键词
急性缺血性脑卒中/恢复/芪蛭通络胶囊/疗效/神经功能Key words
Acute ischemic stroke/Recovery/Qizhi Tongluo cpsules/Efficacy/Neurological function分类
医药卫生引用本文复制引用
张辉,袁磊,王剑宇,赵晨,徐肖杨,王伟,马慧雪..西医常规治疗联合芪蛭通络胶囊对急性缺血性脑卒中介入术后患者恢复的临床研究[J].中国医院用药评价与分析,2023,23(12):1446-1449,4.基金项目
山西省应用基础研究项目面上青年基金项目(No.201801D221429) （No.201801D221429）
