浙江医学2023，Vol.45Issue(24)：2615-2621,7.DOI:10.12056/j.issn.1006-2785.2023.45.24.2023-1474
腹膜透析患者相位角与腹主动脉钙化严重程度的关系及对疾病进展的影响
Correlation between phase angle and severity of abdominal aortic calcification in peritoneal dialysis patients and its influence on disease progression
摘要
Abstract
Objective To explore the correlation between phase angle(PhA)and severity of abdominal aortic calcification(AAC)in peritoneal dialysis(PD)patients and its influence on disease progression.Methods A total of 178 patients undergoing regular peritoneal dialysis in Shaoxing People's Hospital from March 2022 to May 2023 were enrolled.According to the abdominal aortic calcification score(AACS),patients were classified as no calcification(AACS=0 points,n=92),mild calcification(1 point ≤AACS≤4 points,n=44)and moderate to severe calcification(AACS≥5 points,n=42).The body composition was measured by bioelectrical impedance analyzer and the PhA was calculated.The clinical,laboratory,body composition data were collected and compared among three groups.Multivariate logistic regression analysis was used to identify the influencing factors for the severity and progression of AAC.Results There were significant differences in age,dialysis duration,diastolic pressure,diabetes mellitus,alkaline phosphatase,and PhA(all P＜0.05).Multivariate logistic regression analysis showed that age(OR=1.069,95％CI:1.020-1.121,P＜0.01),gender(OR=4.340,95％CI:1.565-12.037,P＜0.01),dialysis duration(OR=1.038,95％CI:1.020-1.057,P＜0.01),comorbidity with diabetes mellitus(OR=3.372,95％CI:1.167-9.743,P＜0.05)and serum homocysteine(OR=1.074,95％CI:1.030-1.120,P＜0.01)were independent risk factors for moderate to severe AAC in PD patients,while PhA(OR=0.442,95％CI:0.228-0.856,P＜0.05)was a protective factor.PhA(OR=0.318,95％CI:0.144-0.705,P＜0.01)and comorbidity with diabetes mellitus(OR=3.705,95％CI:1.122-12.236,P＜0.05)were significantly associated with rapid progression of AAC in PD patients.Conclusion Lower PhA is an independent risk factor for the presence of moderate to severe AAC in PD patients.In addition,low PhA is significantly related to the rapid progression of AAC in PD patients.关键词
腹膜透析/相位角/腹主动脉钙化/疾病进展Key words
Peritoneal dialysis/Phase angle/Abdominal aortic calcification/Disease progression引用本文复制引用
任洲浩,吴佳盈,沈水娟,官继超,丁苗佳,吴少锐,杨燕茹..腹膜透析患者相位角与腹主动脉钙化严重程度的关系及对疾病进展的影响[J].浙江医学,2023,45(24):2615-2621,7.基金项目
浙江省医药卫生科技计划项目(2023KY1244) （2023KY1244）
浙江省卫生健康科技计划项目(2022KY404) （2022KY404）
