川北医学院学报2024，Vol.39Issue(1)：34-37,4.DOI:10.3969/j.issn.1005-3697.2024.01.008
经颅直流电刺激联合运动康复训练对脑卒中患者下肢运动功能和血清Hcy水平的影响
Effects of transcranial direct current stimulation combined with exercise rehabilitation training on lower limb motor function and serum Hcy level in stroke patients
摘要
Abstract
Objective:To investigate the effects of transcranial direct current stimulation(tDCS)combined with exercise reha-bilitation training on lower limb motor function and serum homocysteine(Hcy)levels in stroke patients.Methods:119 stroke patients were divided into control group(n =59)and experimental group(n =60)according to different treatment methods.Both groups were given exercise rehabilitation training.In addition,the experimental group was given tDCS stimulation,and the control group was given tDCS pseudo stimulation.Both groups were treated continuously for 4 weeks.The evaluation data of knee flexion angle,ankle dorsiflexion angle,Fugl-Meyer lower limb motor function assessment scale(FMA-LE),Berg balance scale(BBS),'standing-walking'timing test(TUGT),Holden functional walking classification(FAC),modified Barthel index(MBI)and National Institutes of Health Stroke Scale(NHISS)were compared and analyzed before and after treatment,and serum Hcy levels were detected before and after treatment in the two groups.Results:Compared with the control group,the knee flexion angle,ankle dorsiflexion angle,FMA-LE and BBS scores of the experimental group were higher after treatment(P<0.05).The TUGT and NHISS scores of the experimental group were lower than those of the control group(P<0.05),and the FAC grading and MBI scores were higher than those of the control group(P<0.05).The serum Hcy level in the experimental group was lower than that in the control group(P<0.05).Conclusion:tDCS combined with exercise rehabilitation training can improve the lower limb motor function and walking ability of stroke patients,and reduce the serum Hcy level.关键词
脑卒中/经颅直流电刺激/下肢运动功能/步行能力/同型半胱氨酸Key words
Stroke/Transcranial direct current stimulation/Lower limb motor function/Walking ability/Homocysteine分类
医药卫生引用本文复制引用
王嘉琳,刘立芝,官艳林,冯慧,潘化平..经颅直流电刺激联合运动康复训练对脑卒中患者下肢运动功能和血清Hcy水平的影响[J].川北医学院学报,2024,39(1):34-37,4.基金项目
江苏省科技项目社会发展面上项目(BE2021618) （BE2021618）
南京医科大学科技发展基金项目(NMUB2020156) （NMUB2020156）
