川北医学院学报2024，Vol.39Issue(1)：55-58,4.DOI:10.3969/j.issn.1005-3697.2024.01.013
血小板参数联合Wells评分对肺血栓栓塞症诊断及预后的评估价值
Evaluated value of platelet parameters combined with Wells score in the diagnosis and prognosis of pulmonary thromboembolism
摘要
Abstract
Objective:To explore the evaluated value of platelet parameters combined with clinical prediction score for pulmona-ry embolism(Wells score)in the diagnosis and prognosis of pulmonary thromboembolism(PTE).Methods:120 patients with suspec-ted PTE were enrolled as research subjects.According to the results of multislice CT pulmonary angiography(CTPA),the patients were divided into PTE group(n =88)and non-PTE group(n =32).According to the prognosis within 30 days,the patients in PTE group were further classified into death group(n =18)and survival group(n =70).The platelet parameters[platelet count(PLT),mean platelet volume(MPV),platelet volume distribution width(PDW)]and Wells score of patients with different prognosis in PTE group,non PTE group and PTE groups were compared,the value of Wells score combined with platelet parameters in diagnosing PTE and its correlation with mortality events were analyzed.Results:The PLT in PTE group was lower than that in non-PTE group(P<0.05),while the MPV,PDW and Wells score were higher than those in non-PTE group(P<0.05).ROC curve showed that the sensitivity and specificity of combined diagnosis were80.68%and78.13%.Using CTPA as the gold standard,the accuracy of Wells score combined with platelet parameters in diagnosing PTE was 90.83%.The PLT in death group was lower while the MPV,PDW and Wells score were higher than those in survival group(P<0.05).Correlation analysis showed that the death events in PTE patients were negatively corre-lated with PLT and positively correlated with MPV,PDW and Wells scores(P<0.05).Conclusion:PLT,MPV and PDW combined with Wells score in the diagnosis of PTE has high consistency with CTPA,and it has certain reference value on prognosis judgement.关键词
肺血栓栓塞症/血小板参数/肺栓塞临床预测评分/诊断/预后Key words
Pulmonary thromboembolism/Platelet parameters/Clinical prediction score for pulmonary embolism/Diagnosis/Prognosis分类
医药卫生引用本文复制引用
罗麟洁,刘晟文,张友兰,黎伟..血小板参数联合Wells评分对肺血栓栓塞症诊断及预后的评估价值[J].川北医学院学报,2024,39(1):55-58,4.基金项目
四川省医学青年创新科研项目(Q21048) （Q21048）
