川北医学院学报2024，Vol.39Issue(1)：88-91,4.DOI:10.3969/j.issn.1005-3697.2024.01.021
麻杏石甘汤联合布地奈德与氨溴索对小儿支气管肺炎的治疗疗效
Therapeutic effect of Maxingshigan Decoction combined with budesonide and ambroxol on bronchial pneumonia in children
摘要
Abstract
Objective:To explore the therapeutic effect of Maxingshigan Decoction combined with budesonide and ambroxol on children with bronchial pneumonia,and observe the effects on serum Th1/Th2 cytokines and platelet parameters.Methods:According to the treatment methods,105 children with bronchopneumonia were divided into observation group(treated with Maxingshigan Decoction combined with budesonide and ambroxol,n =50)and control group(treated with budesonide and ambroxol,n =55),the treatment course was 1 week.The therapeutic effect,repair progress(time of fever,cough relief,shortness of breath and lung rales),serum Th1/Th2 cytokines[interferon γ(IFN-γ),interleukin-4(IL-4)],platelet parameters[platelet count(PLT),mean platelet volume(MPV)and platelet distribution width(PDW)]before and after treatment were compared between the two groups.Results:After trentment,the total effective rate of observation group was84.00%,which was higher than that of control group(63.64%,P<0.05).The time of fe-ver,shortness of breath,and lung rales in the observation group were shorter than those in the control group(P<0.05).After treat-ment,serum IFN-γ,peripheral blood PLT and PDW in observation group were lower than those in control group(P<0.05),MPV was higher than that in control group(P<0.05),and serum IL-4 in observation group was lower than that in control group(P>0.05).Conclusion:Maxingshigan Decoction combined with budesonide and ambroxol can effectively improve the clinical symptoms,improve the therapeutic effect,improve the cellular immune response and reduce the blood viscosity of children with bronchophenitis.关键词
麻杏石甘汤/布地奈德/氨溴索/小儿气管肺炎/疗效/细胞免疫/血小板Key words
Maxingshigan decoction/Budesonide/Ambroxol/Tracheopneumonia in children/Curative effect/Cellular immunity/Platelet分类
医药卫生引用本文复制引用
邓慕贞,张智敏,张海霞,刘爱娟,刘俭青..麻杏石甘汤联合布地奈德与氨溴索对小儿支气管肺炎的治疗疗效[J].川北医学院学报,2024,39(1):88-91,4.基金项目
广东省广州市花都区科技计划项目(21-HDWS-076) （21-HDWS-076）
