陈宇 1李响 1宁佳曦 1王雪 1杨适 1王忠琼1
作者信息
- 1. 西南医科大学附属医院消化内科,四川 泸州 646000
- 折叠
摘要
Abstract
Objective:To explore the relationship between score of bedside index of severity in acute pancreatitis(BISAP),neutrophil to lymphocyte ratio(NLR),hematocrit(HCT),serum calcium ion(Ca2+)and severity,prognosis of acute pancreatitis(AP).Methods:A total of 371 patients with AP were selected as the research subjects.According to patient's condition,they were di-vided into mild AP(MAP)group(n =220),moderate to severe AP(MSAP)group(n =111)and severe AP(SAP)group(n = 40).According to prognosis,patients were divided into death group(n =15)and survival group(n =356).The clinical data of pa-tients with different conditions(gender,age,length of hospital stay,hospitalization costs)and laboratory test indicators[neutrophil to lymphocyte ratio(NLR),hematocrit(HCT),Ca2+,AP severity bedside index(BISAP)score]for different conditions and prognoses in the groups were compared between the groups.The relationship between laboratory test indicators and severity and prognosis of AP was analyzed.Results:There were significant differences in NLR,HCT,Ca2+ and BISAP score among the groups(P<0.05).With the ag-gravation of the disease,NLR,HCT and BISAP score were increased,while Ca2+ level was decreased(P<0.05).NLR,HCT and BISAP score in survival group were lower than those in death group,while Ca2+ level was higher than that in death group(P<0.05).ROC curves analysis showed that area under the curve(AUC),sensitivity,and specificity of NLR,HCT,Ca2+ and BISAP score for pre-dicting prognosis of AP patients were[0.857(95%CI:0.817～0.891),0.842(95%CI:0.801～0.878),0.806(95%CI:0.762～0.845),0.870(95%CI:0.831～0.902)],(80.00%,66.67%,73.33%,93.33%)and(92.70%,93.26%,80.06%,76.40%),respectively.All of the four indexes were of good predictive value for prognosis(P<0.05).Conclusion:NLR,HCT,serum Ca2+ and BISAP score can assist in evaluating the severity of AP,which also have certain predictive value for prognosis.关键词
急性胰腺炎/BISAP评分/红细胞比容/钙离子/严重程度/预后Key words
Acute pancreatitis/BISAP score/Hematocrit/Calcium ion/Severity/Prognosis分类
医药卫生
