摘要
Abstract
Objective:To observe the clinical efficacy of intratympanic injection of glucocorticoid in the treatment of Sudden hearing loss(SHL)and analyze its influencing factors.Methods:The clinical data of 108 patients with SHL who were treated 2 weeks with intratympanic injection of glucocorticoid and 108 patients with SHL who 2 weeks received intravenous infusion of glucocorticoid were retrospectively analyzed,and they were divided into observation group and control group according to the different treatment.The patients in observation group cases were divided into cured group(n =52)and uncured group(n =56)by means of the different thera-peutic effects.The clinical efficacy of patients with different treatment methods and general clinical data of the two subgroups were com-pared,such as gender,age,time of onset,affected ear site,complications and degree of hearing loss.The influencing factors of efficacy of intratympanic injection of glucocorticoid in the treatment of SHL were analyzed.Results:After 2 weeks of treatment,the total effective rate in observation group was higher than that in control group(87.04%vs.75.93%,P<0.05).Thedifferencesinage,onset time,co-morbid dizziness,degree of hearing loss,and type of hearing loss among patients with different treatment effects were statistically signifi-cant(P<0.05).Regression analysis showed that the time of onset,vertigo,degree of hearing loss and type of hearing damage were all independent factors affecting the efficacy of intratympanic glucocorticoid injection in treating SHL(P<0.05).Conclusion:Intratym-panic injection of glucocorticoid in the treatment of SHL has a significant efficacy,and the prognosis of patients is affected by the onset time,vertigo,degree of hearing loss,type of hearing damage and other factors.关键词
鼓室内注射/糖皮质激素/突发性耳聋/疗效/影响因素Key words
Intratympanic injection/Glucocorticoid/Sudden hearing loss/Efficacy/Influencing factors分类
医药卫生
