重庆医学2024，Vol.53Issue(1)：93-97,5.DOI:10.3969/j.issn.1671-8348.2024.01.019
hrTMS联合MSS在重型颅脑损伤后慢性意识障碍患者的应用效果分析
Analysis on application effect of hrTMS combined with MSS in patients with prolonged disorders of consciousness after severe traumatic brain injury
摘要
Abstract
Objective To investigate the effect of high-frequency repetitive transcranial magnetic stimu-lation(hrTMS)combined with multi-sensory stimulation(MSS)in the patients with prolonged disorders of consciousness(PDOC)after severe traumatic brain injury(STBI).Methods Ninety-two patients with PDOC caused by STBI in this hospital from March 2020 to November 2022 were selected as the study subjects and e-venly divided into the observation group(conventional treatment+MSS+hrTMS)and control group(con-ventional treatment+MSS)by adopting the random number table method,46 cases in each group.The elec-troencephalogram examination results,Glasgow Coma Scale(GCS),Disability Rating Scale(DRS)and Coma Recovery Scale-revised(CRS-R)scores before intervention and in 2 months after and intervention and the wake-promoting effective rates after intervention were compared between two groups.Results Compared with before intervention,the electroencephalogram(EEG)grade after intervention in the two groups was sig-nificantly improved,moreover the observation group was superior to the control group(P＜0.05).Compared with before intervention,the GCS and CRS-R scores after intervention in the two groups were increased,the DRS score was decreased,moreover the GCS and CRS-R scores in the observation group were higher than those in the control group,while the DRS score was lower than that in the control group(P＜0.05).After in-tervention,the wake-promoting effective rate in the observation group was higher than that in the control group(76.1％vs.54.3％),and the difference was statistically significant(P＜0.05).Conclusion The hrT-MS combined with MSS has good effect for improving PDOC after STBI.关键词
慢性意识障碍/高频重复经颅磁刺激/多感觉刺激疗法/重型颅脑损伤/促醒疗效Key words
prolonged disorders of consciousness/high-frequency repetitive transcranial magnetic stim-ulation/multi-sensory stimulation/severe traumatic brain injury/wake-promoting effect分类
医药卫生引用本文复制引用
周青,孙娟..hrTMS联合MSS在重型颅脑损伤后慢性意识障碍患者的应用效果分析[J].重庆医学,2024,53(1):93-97,5.基金项目
重庆市科卫联合医学科研项目(2022ZDXM002). （2022ZDXM002）
