重庆医学2024，Vol.53Issue(1)：139-144,6.DOI:10.3969/j.issn.1671-8348.2024.01.027
内质网应激在甲基苯丙胺使用障碍中的研究进展
Research advances in endoplasmic reticulum stress in methamphetamine use disorder
摘要
Abstract
Methamphetamine use disorder is an ongoing global public health problem with complex mechanisms involving multiple neural circuits and neurotransmitters in the brain,and there are currently no effective drugs and methods to treat it.This article reviews the role of endoplasmic reticulum stress in meth-amphetamine use disorder and discusses the treatment strategies that can be used to mitigate the methamphet-amine-induced neurotoxic damage,which will contribute to the exploration of methamphetamine use disorder mechanisms and the development of new target drugs.关键词
甲基苯丙胺/神经毒性/内质网应激/未折叠蛋白反应/细胞凋亡/综述Key words
methamphetamine/neurotoxicity/endoplasmic reticulum stress/unfolded protein response/apoptosis/review分类
医药卫生引用本文复制引用
魏涛,焦东亮..内质网应激在甲基苯丙胺使用障碍中的研究进展[J].重庆医学,2024,53(1):139-144,6.基金项目
安徽省自然科学基金项目(1908085MH278) （1908085MH278）
上海市重性精神病重点实验室开放科研项目(13dz2260500). （13dz2260500）
