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不对称C-H/C-H交叉脱氢偶联反应研究进展

李天宇 吴丹清 刘佳俊 徐大振 苗志伟

大学化学2023,Vol.38Issue(12):165-180,16.
大学化学2023,Vol.38Issue(12):165-180,16.DOI:10.3866/PKU.DXHX202305034

不对称C-H/C-H交叉脱氢偶联反应研究进展

Research Progress of Asymmetric C-H/C-H Cross Dehydrogenation Coupling Reaction

李天宇 1吴丹清 1刘佳俊 1徐大振 1苗志伟1

作者信息

  • 1. 南开大学化学学院,元素有机化学国家重点实验室,天津 300071
  • 折叠

摘要

Abstract

In recent years,the cross-dehydrogenative coupling(CDC)reaction has received widespread attention in the field of organic synthetic chemistry.This strategy avoids the pre-functionalization of substrates in the reactions that form carbon-carbon bonds.It demonstrates high atomic economy and aligns with the development requirements of green chemistry.Furthermore,asymmetric CDC reactions can realize stereoselective construction of carbon-carbon bonds,which currently constitutes a key area of research in organic synthesis.This paper reviews the research progress in asymmetric CDC reactions and provides a perspective on the future development direction in this field.

关键词

不对称催化/绿色化学/碳-氢键活化/碳-碳键构筑/研究进展

Key words

Asymmetric catalysis/Green chemistry/C-H activation/C-C bond formation/Research progress

分类

社会科学

引用本文复制引用

李天宇,吴丹清,刘佳俊,徐大振,苗志伟..不对称C-H/C-H交叉脱氢偶联反应研究进展[J].大学化学,2023,38(12):165-180,16.

基金项目

国家自然科学基金面上项目(22071113) (22071113)

福建省南平市科技项目(N2020Z008) (N2020Z008)

大学化学

1000-8438

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