分子影像学杂志2024，Vol.47Issue(1)：83-87,5.DOI:10.12122/j.issn.1674-4500.2024.01.15
菌阴活动性肺结核的多层螺旋CT影像学特征及诊断模型构建
Construction of a diagnostic model for smear-negative active pulmonary tuberculosis based on multi-slice CT imaging features
李欣 1朱小刚 2骆敏霞1
作者信息
- 1. 常州市第三人民医院感染管理科,江苏 常州 213000
- 2. 南京医科大学附属常州第二人民医院皮肤科,江苏 常州 213000
- 折叠
摘要
Abstract
Objective To analyze the multi-slice CT(MSCT)features of patients with smear-negative active pulmonary tuberculosis and construct a diagnostic model.Methods A total of 1016 patients with pulmonary diseases who were admitted to our hospital were enrolled from January 2020 to January 2023,and they were divided into smear-negative pulmonary tuberculosis group(n=478)and non-tuberculous pulmonary disease group(n=538,including 200 cases of lung cancer and 338 cases of pneumonia)according to clinical diagnosis.All patients received MSCT examination,and their MSCT imaging features were analyzed.Logistic regression analysis was conducted to identify the signs related to the diagnosis of smear-negative active pulmonary tuberculosis,and a diagnostic model for smear-negative active pulmonary tuberculosis was constructed.The diagnostic efficiency of the model was evaluated with AUC.Results There were statistically significant differences in MSCT signs such as tree in bud,centrilobular nodule,cavity,calcification and lobulation between the two groups(P<0.05).Logistic regression analysis found that tree in bud sign,centrilobular nodule and cavity were independent risk factors for smear-negative active pulmonary tuberculosis(P<0.05).The equation of the combined diagnosis model constructed based on logistic regression analysis was as follow:Log(P)=-1.256+1.455×tree in bud sign+0.982×centrilobular nodule+1.023×cavity.The AUC,sensitivity and specificity of this model were 0.825,93.94%and 70.97%,respectively.Conclusion The diagnostic model constructed based on MSCT imaging features is of high value in diagnosis of smear-negative active pulmonary tuberculosis and can provide a reliable basis for clinical diagnosis and treatment of the disease.关键词
计算机断层扫描/多层螺旋/影像学特征/菌阴活动性肺结核/诊断模型/诊断价值Key words
computed tomography/multi-slice spiral/imaging feature/smear-negative active pulmonary tuberculosis/diagnostic model/diagnostic value引用本文复制引用
李欣,朱小刚,骆敏霞..菌阴活动性肺结核的多层螺旋CT影像学特征及诊断模型构建[J].分子影像学杂志,2024,47(1):83-87,5.
