国际老年医学杂志2024，Vol.45Issue(1)：92-95,4.DOI:10.3969/j.issn.1674-7593.2024.01.017
细胞焦亡在肌少性肥胖中的作用机制及研究进展
Advancements in Understanding the Molecular Mechanisms of Pyroptosis in Sarcopenic Obesity:a Comprehensive Research Overview
摘要
Abstract
In an era of global population aging and a rising prevalence of obesity,the complex condition known as sar-copenic obesity(SO)has emerged as a subject of growing interest and concern.A relatively recent discovery,pyroptosis,a form of programmed cell death characterized by the activation of inflammasomes and the subsequent release of a multitude of inflammatory me-diators,has garnered increasing attention.Emerging research suggests that pyroptosis plays a pivotal role in the intricate development and progression of SO.Understanding the intricate relationship between SO and pyroptosis holds the potential to shed light on the un-derlying mechanisms driving SO's pathogenesis.Such insights not only contribute to a deeper comprehension of SO but also offer valua-ble guidance for the development of targeted therapeutic interventions.关键词
肌少性肥胖/焦亡/肥胖/肌少症/衰老Key words
Sarcopenic obesity/Pyroptosis/Obesity/Sacorpenia/Aging引用本文复制引用
付婉瑞,古再丽努尔·卡德尔,何雅琦,冯颖..细胞焦亡在肌少性肥胖中的作用机制及研究进展[J].国际老年医学杂志,2024,45(1):92-95,4.基金项目
上海市卫生健康系统重要薄弱学科建设计划(2019ZB0102) （2019ZB0102）
