广州医药2024，Vol.55Issue(1)：1-8,53,9.DOI:10.3969/j.issn.1000-8535.2024.01.001
结直肠癌的早期诊断策略和治疗进展
Early diagnostic strategies and therapeutic advances in colorectal cancer
摘要
Abstract
The incidence of colorectal cancer(CRC)can be reduced through screening and early detection.Effective resection of tumor lesions reduces mortality from CRC.Although progress has been made in understanding the risk factors,pathogenesis and precursor lesions of CRC,the reasons for the recent increase in the incidence of CRC in young adults are largely unknown.A variety of invasive,semi-invasive and non-invasive screening modalities have emerged in the last decade.The current emphasis on the quality of colonoscopy has improved the effectiveness of screening,and the role of new imaging technologies such as artificial intelligence in tumor detection is rapidly emerging.Moreover,there are effective interventions for CRC,such as new surgical modalities for anal preservation therapy,and new advances in the field of targeted therapy and immunotherapy,which have been shown to improve the survival rate of CRC.The aim of this article is to summarize the current evidence on CRC screening modalities and guidelines both nationally and internationally,and to provide an overview of advances in the field of CRC treatment.关键词
结直肠癌/筛查/早期诊断/手术治疗/靶向治疗Key words
colorectal cancer/screening/early diagnosis/surgical treatment/targeted therapy引用本文复制引用
黄庆,索彩霞,何凤,罗青青,李旺林,曹杰..结直肠癌的早期诊断策略和治疗进展[J].广州医药,2024,55(1):1-8,53,9.基金项目
国家自然科学基金(81871943,82173236) （81871943,82173236）
广东省科技计划项目(2020B1111170004,202206080008) （2020B1111170004,202206080008）
