广州医药2024，Vol.55Issue(1)：85-90,105,7.DOI:10.3969/j.issn.1000-8535.2024.01.015
Wnt/β-catenin信号通路在心肌纤维化中的作用研究进展
Research progress on the role of Wnt/β-catenin signaling pathway in myocardial fibrosis
摘要
Abstract
The Wnt/β-catenin signaling pathway is a family of proteins that play a key role in embryonic development,cell proliferation and differentiation,migration,stem cell renewal,etc.Dysfunctions of Wnt/β-catenin signaling pathway often lead to various serious diseases,such as tumor,heart,lung,liver,bone and neurological diseases,etc.Numerous studies have shown that the Wnt/β-catenin signaling pathway plays an important role in the pathogenesis of cardiac fibrosis.This article,in combination with the latest research findings,presents a review of the Wnt/β-catenin pathway from the perspective of myocardial fibrosis-related diseases,in order to provide new ideas for preventing myocardial fibrosis and achieving the goal of combating cardiovascular disease.关键词
Wnt/β-catenin/心肌纤维化/心血管疾病Key words
Wnt/β-catenin/myocardial fibrosis/cardiovascular disease引用本文复制引用
高雅婷,邱对鑫,高磊,石开虎..Wnt/β-catenin信号通路在心肌纤维化中的作用研究进展[J].广州医药,2024,55(1):85-90,105,7.基金项目
国家自然科学基金(82304941) （82304941）
