阿司匹林抗血小板相关基因多态性在汉族NSTEMI患者人群中的分布OACSTPCD
Distribution of gene polymorphisms associated with aspirin antiplatelet in the Han NSTEMI population
目的:分析汉族非ST段抬高型心肌梗死(NSTEMI)患者人群中与阿司匹林抗血小板药理作用相关的GPⅢa PLA2(rs5918)、PEAR1(rs12041331)和PTGS1(rs10306114)基因的基因型结果及等位基因分布特征,为汉族NSTEMI患者的个体化治疗提供参考.方法:选取2016年1月～2022年12月首都医科大学附属北京潞河医院收治的汉族NSTEMI患者107例为研究对象.采用荧光染色原位杂交的方法对GPⅢa PLA2(rs5…查看全部>>
Objective:To analyze the genotype and allele distribution characteristics of GPⅢa PLA2(rs5918),PEAR1(rs12041331),and PTGS1(rs10306114)genes related to the antiplatelet pharmacological effects of aspirin,providing reference for individualized treatment of Chinese Han NSTEMI patients.Methods:A total of 107 Han patients with NSTEMI in Beijing Luhe Hospital affiliated to Capital Medical University from January 2016 to December 2022 were selected as the research …查看全部>>
李六水;王飞;周澳;杨青;刘宪军
首都医科大学附属北京潞河医院,北京 101149上海市金山区中西医结合医院,上海 201501首都医科大学附属北京潞河医院,北京 101149北京市朝阳区东坝第二社区卫生服务中心,北京 100015首都医科大学附属北京潞河医院,北京 101149
药学
阿司匹林抗血小板非ST段抬高型心肌梗死基因多态性基因型分布
AspirinAntiplateletNon-ST-segment elevation myocardial infarctionGene polymorphismGenotype dis-tribution
《海南医学院学报》 2024 (2)
106-112,7
This study was supported by Capital Clinical Characteristic Application Research Project(Z181100001718144)Beijing Tongzhou District Science and Technology Plan Project(KJ2017CX036-06)In-hospital Project of Shanghai Jinshan District Integrated Traditional Chinese and Western Medicine Hospital(2022-1) 首都临床特色应用研究项目(Z181100001718144)北京市通州区科技计划项目(KJ2017CX036-06)上海市金山区中西医结合医院院内课题(2022-1)
评论