不同干预措施对正畸牙齿移动加速效果的网状meta分析OACSTPCD

Objective:To explore the effectiveness of various interventions in accelerating tooth movement,a systematic review and net-work meta analysis were used to draw a conclusion.Methods:MEDLINE,EMBASE,Willey Library,EBSCO,Web of Science Databases,and Cochrane Central Register of Controlled Trials databases to identify relevant studies.ADDIS 1.16.6 and Stata 16.0 software were used for NMA.Results:Five thousand five hundred and forty-two articles were searched out.After screening by two independent investigators,forty-seven randomized controlled trials,1 390 participants,were included in this network meta-analysis.A total of 11 interventions involving Piezocision(Piezo),Photobiomodulation therapy(PBMT),Plate-let-rich plasma(PRP),Electromagnetic field(EF),Low intensity laser therapy(LLLT),Low intensity pulsed ultrasound(LI-PUS),Low-frequency vibrations(LFV),Distraction osteogenesis(DAD),Corticotomy(Corti),Micro-osteoperforations(MOPS),Traditional orthodontic(OT)were identified and classified into 3 classes including surgical treatment,non-surgical treatment and traditional orthodontic treatment.According to SUCRA probability ranking of the best intervention effect,when orthodontic treatment lasted for 1 month,PBMT(90.6%),Piezo(87.4%)and MOPs(73.6%)were the top three interventions to improve the efficiency of canine tooth movement.When orthodontic treatment lasted for 2 months,Corti(75.7%),Piezo(69.6%)and LFV(58.9%)were the top three interventions for improving the mobility efficiency of canine tooth movement.When orthodontic treatment lasted for 3 months,Corti(73.3%),LLLT(68.4%)and LFV(60.8%)were the top three interven-tions for improving the mobility efficiency of canine tooth movement.Conclusion:PBMT and Piezo can improve the efficiency of canine tooth movement significantly after 1 month,while Corti and LFV can improve the efficiency of canine tooth movement bet-ter after 2 and 3 months.