全腔镜下乳晕入路甲状腺全切术治疗甲状腺乳头状癌对甲状旁腺功能的影响OACSTPCD

Objective:To investigate the impact of transareolar endoscopic thyroidectomy on parathyroid function in the treatment of papillary thyroid carcinoma.Methods:Clinical data of 130 patients with bilateral micro papillary thyroid carcinoma who underwent total thyroidectomy from March 2020 to January 2023 at the Affiliated Hospital of Chengde Medical College were collected and retrospectively analyzed.Among them,30 cases underwent total thyroidectomy with central lymph node dissection through the transareolar route,and 100 cases underwent total thyroidectomy with central lymph node dissection through the traditional neck approach.Serum parathyroid hormone and blood calcium levels were compared between the two groups before surgery and at 1 day,7 days,1 month,3 months,and 6 months after surgery.Results:There was no statistically signifi-cant difference in serum parathyroid hormone and blood calcium levels between the two groups before surgery,at 1 day,7 days,3 months,and 6 months after surgery(P>0.05).At 1 month after surgery,there was a statistically significant difference in serum parathyroid hormone and blood calcium levels between the two groups(P<0.05),with a greater decrease in the transareolar surgery group(P<0.05).Calcium supplemen-tation was given orally or intravenously after surgery.After 6 months,4 cases in the transareolar approach group had serum parathyroid hormone levels<15 pg/mL,while 11 cases in the traditional approach group had levels<15 pg/mL.After 6 months,2 cases in the transareolar approach group had blood calcium levels<2.0 mmoL/L,while 4 cases in the traditional neck approach group had levels<2.0 mmoL/L.Conclusion:For to-tal thyroidectomy,there was no statistically significant difference in the incidence of permanent parathyroid dysfunction between transareolar endoscopic thyroidectomy and traditional open neck approach.For patients with cosmetic needs,transareolar endoscopic thyroidectomy is a safe and effective surgical approach.