河北医学2024，Vol.30Issue(1)：130-134,5.DOI:10.3969/j.issn.1006-6233.2024.01.026
血液粘度网织血小板及血小板参数检测对老年免疫性血小板减少症的诊断价值
Diagnostic Value of Blood Viscosity Reticulated Platelets and Platelet Parameters in Elderly Immune Thrombocytopenia
摘要
Abstract
Objective:To explore the diagnostic value of blood viscosity,reticulated platelets,and platelet parameters in elderly patients with immune thrombocytopenia(ITP).Methods:A total of 82 elderly(age 60 and above)ITP patients from our hospital between 2020 and 2022 were included as the observation group.The control group included 50 elderly patients with non-immune thrombocytopenia(NITP)(25 cases with cirrhosis,15 cases with hematological diseases,and 10 cases with other tumors).Another 50 elderly health examination participants were included as the second control group.Blood samples were collected for blood rheology analysis,including blood viscosity using a hemorheology analyzer,and platelet parameters[platelet distribution width(PDW),mean platelet volume(MPV),platelet-large cell ratio(P-LCR)]u-sing an automated hematology analyzer.Comparative analysis of blood viscosity,reticulated platelets,PDW,MPV,and P-LCR before and after treatment was performed.Results:Before treatment,the observation group showed higher PDW,MPV,and reticulated platelet ratio compared to both control groups,while blood viscos-ity was lower,with statistical significance(P<0.05).There was no significant difference between Control Group 1 and Control Group 2(P>0.05).As the platelet count decreased in the observation group,PDW and MPV increased,and blood viscosity decreased,showing statistically significant differences between the obser-vation group and the control groups(P<0.05).Comparative analysis before and after treatment showed that in the observation group,the blood viscosity and platelet count of severe and mild-to-moderate patients in-creased after treatment(P<0.05),while reticulated platelets,P-LCR,PDW,and MPV significantly de-creased and were lower than before treatment,with statistical significance(P<0.05).Conclusion:Determi-ning blood viscosity,reticulated platelets,and platelet parameters significantly contributes to the etiological di-agnosis and disease assessment of elderly ITP patients.Additionally,it plays a positive role in prognosis eval-uation,providing ample diagnostic support for clinical practice.关键词
免疫性血小板减少症/老年/血液粘度/网织血小板/血小板参数Key words
Immune thrombocytopenia/Elderly/Blood viscosity/Reticulated platelets/Platelet parameters引用本文复制引用
杨秋婷,朱艳君,范永丽..血液粘度网织血小板及血小板参数检测对老年免疫性血小板减少症的诊断价值[J].河北医学,2024,30(1):130-134,5.基金项目
河北省承德市2022年承德市科学技术研究与发展计划项目,(编号:202204A020号) （编号:202204A020号）
