化工矿物与加工2024，Vol.53Issue(1)：8-14,7.DOI:10.16283/j.cnki.hgkwyjg.2024.01.002
硅烷化银涂层钛植入物的抗菌改性研究
Study on antibacterial modification of silanized silver coated titanium implants
摘要
Abstract
The surface modification of titanium implants needs to meet the requirements of antibacterial and biocom-patibility in order to ensure the success of implantation.The morphological characteristics,antibacterial properties,and biocompatibility of titanium surfaces were studied using different surface modification methods.The results showed that after acid etching and alkali thermal modification,uniformly distributed three-dimensional network struc-ture was formed on the surface of titanium sheets,which improved their hydrophilicity and roughness,enhanced their biological activity,and promoted cell adhesion;Silver nanoparticles were successfully prepared by chemical reaction of silver nitrate and trisodium citrate.The titanium sheets treated with silane were immersed in a synthesized nano silver solution,and silver loaded antibacterial coating was successfully constructed on the surface of the titanium sheets.At the same time,titanium sheets subjected to acid etching,alkali heat treatment,and silanization modification for 2 hours showed the highest antibacterial and biocompatibility of silver coated titanium substrates.The research results can provide reference for the production of medical titanium implants.关键词
硅烷化/银纳米粒子/微纳米结构/抗菌性/生物相容性Key words
silanization/silvernano particles/micro-nano structure/antibacterial property/bio-compatibility分类
通用工业技术引用本文复制引用
赵波,马凤仓,何代华,侯中中..硅烷化银涂层钛植入物的抗菌改性研究[J].化工矿物与加工,2024,53(1):8-14,7.基金项目
上海市自然科学基金项目(17ZR1419600). （17ZR1419600）
