激光生物学报2023，Vol.32Issue(6)：481-491,516,12.DOI:10.3969/j.issn.1007-7146.2023.06.001
猴痘病毒的分类、演化和宿主范围:痘病毒的系统综述和分析
The Taxonomy,Evolution and Host Spectrum of Mpox Virus:a Systematic Review and Analysis of Poxvirus
摘要
Abstract
The sporadic outbreaks of human mpox diseases in the nearly twenty years have seriously influenced the public health and economic.Though the reservoirs of mpox virus(MPXV)are mainly rodents,it could spill over to humans by direct contact and cause self-limiting infection with the symptom of lymphadenopathy and rash on the skin.Since the first case report-ed outside Africa in the USA at the beginning of this century in America,MPXV has been gradually prevalent globally and be-come an increasing public threat.With the advancing technology of viral detection and gene sequencing,many novel poxviruses were detected which enriched the variety of Poxviridae family.In this review,we provide a comprehensive overview on the lat-est classification,host spectrum,genome feature,pathogenicity and the evolution of MPXV and other poxviruses.This informa-tion will promote our understanding of the phylogenetic relationship and infectious transmission of pathogenic poxviruses and contribute to future viral researches and disease control.关键词
痘病毒/致病性/分类/宿主/遗传演化Key words
poxvirus/pathogenicity/taxonomy/host/evolution分类
医药卫生引用本文复制引用
杨琛晖,葛行义..猴痘病毒的分类、演化和宿主范围:痘病毒的系统综述和分析[J].激光生物学报,2023,32(6):481-491,516,12.基金项目
国家自然科学基金项目(32041001) （32041001）
湖南大学资助项目(521119400156). National Natural Science Foundation of China(32041001) （521119400156）
Hunan University Grant(521119400156). （521119400156）
