兰州大学学报（医学版）2023，Vol.49Issue(11)：61-66,6.DOI:10.13885/j.issn.1000-2812.2023.11.009
冠心病患者冠状动脉周围脂肪CT衰减值与斑块特征的关系
Relationship between CT attenuation values of pericoronary fat and plaque characteristics in patients with coronary heart disease
摘要
Abstract
Objective To investigate the relationship between different plaque features and the attenuation val-ue of computed tomography(CT)of peri-coronary adipose tissue around plaques.Methods 188 patients with stable coronary heart disease(280 lesions)who received coronary CT angiography in The Second Hospital of Lanzhou University from March to July 2021 were retrospectively collected.Artificial intelligence semi-automatic software was used to calculate all the fat attenuation index(FAI)of plaques and their surroundings,analyze the differences,and evaluate the correlation with different plaque features using multiple linear regres-sion.Results Univariate analysis showed that body mass index was positively correlated with pericoronary FAI(r = 0.251,P = 0.016).FAI was higher around vulnerable plaques[(-72.58±5.77)HU],non-calcified plaques[(-74.19±10.18)HU]and mixed plaques[(-77.43±8.56)HU]than around dense calcified plaques[(-86.93±10.01)HU](P<0.001).The FAI of mildly stenosis plaques[(-80.24±12.29)HU]and moderately stenosis plaques[(-79.31±14.56)HU]were lower than those of mildly stenosis plaques[(-84.14±9.41)HU](P<0.05).FAI in middle and distal plaques[(-80.24±12.29)HU]and distal plaques[(-72.95±12.04)HU]were lower than those in proximal plaques[(-83.95±11.59 HU)](P<0.05).There was no correlation be-tween periplaque FAI and plaque length(P>0.05).The results of multiple linear regression analysis showed that FAI was positively correlated with the type and location of plaques in the distal and distal segments(P<0.001).Conclusion FAI around coronary plaque is closely related to plaque type and location,and the selection of FAI around plaques with a high risk of inflammation is helpful to monitor the risk of coronary heart disease progression.关键词
冠心病/冠状动脉周围脂肪组织/斑块成分/计算机断层扫描/脂肪衰减指数/斑块类型Key words
coronary heart disease/periprosthetic adipose tissue/plaque composition/computed tomography/fat attenuation index/plaque type分类
医药卫生引用本文复制引用
席华泽,景梦园,袁隆,徐敏,杨晶晶,周俊林..冠心病患者冠状动脉周围脂肪CT衰减值与斑块特征的关系[J].兰州大学学报（医学版）,2023,49(11):61-66,6.基金项目
国家自然科学基金资助项目(8237191482) （8237191482）
