临床肝胆病杂志2024，Vol.40Issue(1)：169-174,6.DOI:10.12449/JCH240128
肝硬化并发门静脉血栓的危险因素与防护策略
Portal vein thrombosis in liver cirrhosis:Risk factors and protection strategies
摘要
Abstract
Portal vein thrombosis(PVT)is one of the common complications during the natural course of liver cirrhosis and has an important influence on the progression of liver cirrhosis.This article mainly summarizes the research advances in the risk factors for PVT.There are many risk factors for PVT,and Virchow's triad,namely venous stasis,hypercoagulability,and vascular endothelial injury and systemic inflammation caused by surgery or trauma,are considered the main reasons for the development and progression of PVT.At present,more prospective studies are still needed to validate the predictive models for the risk of PVT that have certain application prospects in clinical practice.Cirrhotic patients with PVT tend to have a poor prognosis,and complete obstructive PVT is associated with increased mortality after liver transplantation.Recent studies have shown that prophylactic anticoagulant therapy is safe and effective in patients with liver cirrhosis and can thus help with the prevention and treatment of PVT.关键词
肝硬化/门静脉/静脉血栓形成Key words
Liver Cirrhosis/Portal Vein/Venous Thrombosis引用本文复制引用
冯文娟,周宁,汪雨露,白兆琴..肝硬化并发门静脉血栓的危险因素与防护策略[J].临床肝胆病杂志,2024,40(1):169-174,6.基金项目
甘肃省科技厅重点研发项目(21YF5FA169) （21YF5FA169）
兰州市人才创新创业项目(2021-RC-107) Key Research and Development Project of Science and Technology Department of Gansu Province(21YF5FA169) （2021-RC-107）
Lanzhou Talent Innovation and Entrepreneurship Project(2021-RC-107) （2021-RC-107）
