临床肝胆病杂志2024，Vol.40Issue(1)：193-198,6.DOI:10.12449/JCH240132
半乳糖凝集素-9(Gal-9)介导的免疫调节作用在肝脏疾病中的研究进展
Research advances in the immunomodulatory mechanism of galectin-9 and its role in liver diseases
摘要
Abstract
Galectin-9(Gal-9)is a member of the galectin family that can specifically recognize and bind to galactosides.Recent studies have shown that Gal-9 is highly expressed in the liver and can help to maintain intrahepatic immune homeostasis and perform biological functions in various liver diseases.This article reviews the immunomodulatory functions of Gal-9 and its role in different liver diseases.Studies have shown that Gal-9 has important biological functions in different liver diseases through multiple pathways.Research on the specific immunomodulatory mechanisms and functions of Gal-9 may help to discover the therapeutic role of Gal-9 in liver diseases.关键词
半乳糖凝集素-9/免疫调节/肝脏疾病Key words
Galectin-9/Immunomodulation/Liver Diseases引用本文复制引用
凌珺,朱冰,陈威巍,王卓然,余丽梅,游绍莉..半乳糖凝集素-9(Gal-9)介导的免疫调节作用在肝脏疾病中的研究进展[J].临床肝胆病杂志,2024,40(1):193-198,6.基金项目
国家科技重大专项资助(2017ZX10203201) （2017ZX10203201）
国家重点研发计划资助(2021YFC2301801) National Science and Technology Major Project(2017ZX10203201) （2021YFC2301801）
Funded Projects of National Key R&D Program(2021YFC2301801) （2021YFC2301801）
