临床肝胆病杂志2024，Vol.40Issue(1)：204-207,4.DOI:10.12449/JCH240134
胰管高压导致高脂血症性急性胰腺炎的发病机制
The pathogenesis of hyperlipidemic acute pancreatitis caused by pancreatic duct hypertension
冯佳晨 1张平1
作者信息
- 1. 吉林大学第一医院普通外科中心-肝胆胰外一科,长春 130021
- 折叠
摘要
Abstract
Compared with acute pancreatitis caused by other factors,hyperlipidemic acute pancreatitis often has a higher rate of severe conditions,greater difficulties in predicting prognosis,and a more complex and unclear pathogenesis.At present,the pathogenesis of hyperlipidemic acute pancreatitis may be associated with the elevation of serum free fatty acids,but the lipid-lowering treatment regimens do not reduce the incidence rate of this disease.Recent studies have further confirmed that pancreatic duct hypertension is an important pathogenesis of acute pancreatitis.The latest research advances have shown that hyperlipidemia can lead to pancreatic duct obstruction by causing pancreatic duct hyperplasia,forming protein embolism at the biliary-pancreatic junction,and damaging the secretory function of the pancreatic duct,while pancreatic duct obstruction can in turn cause pancreatic duct obstruction.This article reviews the latest research advances in hyperlipidemia in causing pancreatic duct obstruction and emphasizes that pancreatic duct hypertension is one of the important pathogeneses of hyperlipidemic acute pancreatitis,which will provide new ideas for exploring the pathogenesis of hyperlipidemic acute pancreatitis.关键词
胰腺炎/胰管高压/高脂血症Key words
Pancreatitis/Pancreatic duct hypertension/Hyperlipidemias引用本文复制引用
冯佳晨,张平..胰管高压导致高脂血症性急性胰腺炎的发病机制[J].临床肝胆病杂志,2024,40(1):204-207,4.
