临床眼科杂志2023，Vol.31Issue(6)：488-493,6.DOI:10.3969/j.issn.1006-8422.2023.06.002
远视性弱视儿童视盘周围血管密度变化与黄斑厚度的相关性
Correlation between vascular density around optic disc and macular thickness in children with hyperopic am-blyopia
摘要
Abstract
Objective To investigate the correlation between the changes of perioptic disc vascular density and macular thickness in children with hyperopic amblyopia.Methods Retrospective case-control study.89 childrens with hy-peropic amblyopia treated in our hospital from June 2019 to June 2022 were selected as amblyopia group.In the same peri-od,45 non-amblyopic childrens with normal vision in our hospital were selected as the control group.The general data of children,blood vessel density around optic disc and macular thickness were collected.The statistical differences between the two groups were compared.Spearman correlation analysis was used to analyze the relationship between the changes of perioptic disc vascular density,macular thickness and clinical data.Results Compared with the control group,the length of ocular axis and the area of optic disc were smaller and the diopter was higher in amblyopia group(P＜0.05).The com-parison of macular thickness in each region showed that the thickness of macular fovea,above the inner ring,the nasal side of the inner ring,the lower part of the inner ring and the outer ring in the amblyopia group was larger than that in the con-trol group(P＜0.05).There was a positive correlation between macular central fovea thickness and diopter,but a negative correlation between macular fovea thickness and ocular axis length and optic disc area.There was a negative correlation be-tween the macular thickness of the inner ring and the length of the ocular axis.The blood vessel density around the optic disc in each region showed that the blood vessel density above the optic disc and the nasal side of the optic disc in the am-blyopia group were lower than those in the control group(P＜0.05).The blood vessel density above the optic disc was pos-itively correlated with the length of ocular axis and the area of optic disc,but negatively correlated with diopter.The blood vessel density of the nasal side of the optic disc was positively correlated with the length of the optic axis and the area of the optic disc,but negatively correlated with the diopter.The Spearman correlation analysis showed that the vascular density a-bove the optic disc was negatively correlated with the macular fovea thickness and the macular thickness above the outer ring.The vascular density of the nasal side of the optic disc was negatively correlated with the thickness of the macular fovea and the thickness of the macular on the nasal side of the outer ring(P＜0.05).Conclusions The macular fovea,the upper part of the inner ring,the nasal side of the inner ring,the lower part of the inner ring and the nasal side of the outer ring were thicker in children with amblyopi-a.However,the blood vessel density above the optic disc and the nasal side of the optic disc were lower.Macular thickness and vascular density around the optic disc were correlated with axial length,optic disc area and diopter.The vascular densi-ty above the optic disc was negatively correlated with the macular fovea thickness and the macular thickness above the outer ring.The vascular density of the nasal side of the optic disc was negatively correlated with the thickness of the macular fovea and the thickness of the macular on the nasal side of the outer ring.关键词
远视性弱视/视盘周围血管密度/黄斑厚度Key words
Hyperopic amblyopia/Vascular density around the optic disc/Macular thickness引用本文复制引用
吕维娜,黄灿,雷先明,余素英..远视性弱视儿童视盘周围血管密度变化与黄斑厚度的相关性[J].临床眼科杂志,2023,31(6):488-493,6.基金项目
四川省医学会青年创新科研课题(S21032) （S21032）
