摘要
Abstract
Objective To explore the application of ultra-wide-angle fluorescein fundus angiography(UWFA)in the identification of diabetic retinopathy(DR)neovascular and macular oedema.Methods A retrospective case series study.102 patients(184 eyes)with DR admitted to our hospital from June 2020 to March 2022 were selected,with an av-erage age of(55.63±2.39)years and an average course of(5.13±1.39)years.All patients underwent UWFA and standard 7 visual field(7SF)examinations,and were divided into UWFA group and 7SF group.The observation range of the two detection methods,the detection and staging of retinopathy,the detection of 5 DR fundus lesions,and the examina-tion results of macular oedema were compared and analysed.Through the subjects'work special the eigen(ROC)curve an-alyses the efficiency of UWFA and 7SF and the combination of DR detection.Results UWFA was significantly higher than 7SF in terms of retinal nonperfusion(NP)area,retinal visual area,retinal laser photocoagulation area and retinal neovas-cularization(NV)area area,while the average time was significantly lower than 7SF(P＜0.05).UWFA detection accu-racy of disease degree was 95.11％(175/184),significantly higher than 88.59％(163/184)of 7SF,with significant difference(P＜0.05).UWFA for five DR fundus lesions(retinal neovascularisation,micro haemangioma,no perfusion area,macular oedema,macular arch ring junction)The detection rate of structural change is significantly higher than 7SF(P＜0.05).The detection rate of focal macular oedema,diffuse macular oedema and macular ischaemia by UWFA is sig-nificantly higher than 7SF(P＜0.05).The area under the ROC curve,positive prediction value,negative prediction val-ue,Ling The sensitivity and specificity are significantly higher than 7SF,which has better diagnostic efficiency,and the combined detection effect of the two is better than that of individual detection.Conclusions UWFA is used to achieve DR classification based on neovascular and macular oedema,and the accuracy and accuracy of UWFA are higher than 7SF,which can reliably identify diabetic retinopathy in clinical trials.关键词
超广角荧光素眼底血管造影/糖尿病视网膜病变/新生血管/黄斑水肿Key words
Ultra-widefield fluorescein angiography/Diabetic retinopathy/Neovascular/Macular oedema
