摘要
Abstract
Objective To investigate the relationship between ocular hemodynamics and visual function in patients with glaucoma by color doppler ultrasound.Methods A retrospective case-control study.110 patients with glaucoma ad-mitted to our hospital from March 2020 to March 2022 were selected as the study group,and 110 healthy people who were examined in our hospital at the same time were selected as the control group.According to the degree of visual field dam-age,glaucoma patients were divided into three subgroups:mild group(n=43),moderate group(n=35)and severe group(n=32).The hemodynamics of ophthalmic artery(OA),central retinal artery(CRA)and short posterior ciliary artery(SPCA)in glaucoma group and control group were detected by color doppler ultrasound,and the hemodynamic differences between different subgroups were compared.The risk factors of visual field damage in glaucoma patients were analyzed by multifactorial logistic regression,and the effectiveness of the model was evaluated.Results Peaksy stolic ve-locity(PSV),end diastolic velocity(EDV)and mean velocity(MV)of OA,CRA and SPCA in the glaucoma group were significantly lower than those in the control group(P＜0.05),and pulsatility index(PI)and resistance index(RI)were significantly higher than those in the control group(P＜0.05).PSV,EDV and MV of OA,CRA and SPCA in the severe group were significantly lower than those in the mild group and moderate group(P＜0.05).PSV,EDV and MV of OA,CRA and SPCA in moderate group were significantly lower than those in the mild group(P＜0.05).Low CRA-PSV,low CRA-EDV,low SPCA-PSV and low SPCA-EDV were independent risk factors of visual field damage in glaucoma patients(P＜0.05).Mean defect(MD)in the mild group was negatively correlated with PSV in OA,CRA and SPCA.MD in the moderate group was negatively correla-ted with PSV and EDV of OA,CRA and SPCA.MD in the severe group was significantly negatively correlated with PSV and EDV of OA,CRA and SPCA,and was significantly positively correlated with RI of OA,CRA and SPCA.Back propagation(BP)neural network model has good discrimination and accuracy.Conclusions There is a correlation between the postocular hemodynamics and the degree of visual field damage in patients with glaucoma.Low CRA-PSV,low CRA-EDV,low SPCA-PSV and low SPCA-EDV are independent risk factors of visual field damage in patients with glaucoma.关键词
彩色多普勒超声/青光眼/血流动力学/视觉功能/预测模型Key words
Color doppler ultrasound/Glaucoma/Hemodynamics/Visual function/Prediction model
