西南医科大学学报2024，Vol.47Issue(1)：10-14,5.DOI:10.3969/j.issn.2096-3351.2024.01.003
肝硬化患者代谢特征及营养素与肝再生的关系
Metabolic characteristics of cirrhotic patients and the relationship between nutrients and liver regeneration
摘要
Abstract
The disease progression and complications of liver cirrhosis patients are closely related to nutritional status.The inci-dence rate of malnutrition in liver cirrhosis patients is relatively high,and the prognosis of patients with sarcopenia is even worse.Its metabolic characteristics are the impairment of nutrient intake,absorption and anabolism,and the high metabolic consumption state as-sociated with increased intestinal loss and increased levels of proinflammatory cytokines.Early clinical identification of adverse meta-bolic states and timely intervention are crucial for the progression of liver cirrhosis in patients.Nutrients,including glucose,amino ac-ids,and fat,may have an impact on the course of liver cirrhosis by influencing the process of liver regeneration,and the related mecha-nisms are complex and worthy of further research.Whether regulating the regenerative ability of residual normal liver tissue through nu-trient supplementation intervention can slow down or even reverse the progression of liver cirrhosis and improve survival rate is an im-portant direction for future basic and clinical research.This article provided a review of the metabolic characteristics of patients with liver cirrhosis and the relationship between nutrients and liver regeneration,aiming to serve as a reference for clinical research.关键词
肝硬化/营养不良/营养素/肌少症/肝再生Key words
Liver cirrhosis/Malnutrition/Nutrients/Sarcopenia/Liver regeneration分类
医药卫生引用本文复制引用
李梦迪,陈源文..肝硬化患者代谢特征及营养素与肝再生的关系[J].西南医科大学学报,2024,47(1):10-14,5.基金项目
国家自然科学基金(81970511,82270620) （81970511,82270620）
