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终末期肝病肌少症及其营养干预研究进展

李智鹏 朱姝 罗秋敏 许文雄 张烨琼 郑杏容 谢婵 彭亮

西南医科大学学报2024,Vol.47Issue(1):15-19,5.
西南医科大学学报2024,Vol.47Issue(1):15-19,5.DOI:10.3969/j.issn.2096-3351.2024.01.004

终末期肝病肌少症及其营养干预研究进展

Sarcopenia and nutritional intervention in end-stage liver disease

李智鹏 1朱姝 1罗秋敏 1许文雄 1张烨琼 1郑杏容 1谢婵 1彭亮2

作者信息

  • 1. 中山大学附属第三医院感染性疾病科(广州 510630)
  • 2. 中山大学附属第三医院感染性疾病科(广州 510630)||广东省肝脏病重点实验室(广州 510630)
  • 折叠

摘要

Abstract

In several decades,Sarcopenia has been a focus of medical disciplines.Due to malnutrition and mediators in the liver-muscle axis,sarcopenia is common in patients of end-stage liver disease and is associated with a wide spectrum of adverse out-comes including hepatic decompensation,death and adverse posttransplant outcomes..CT is considered to be a gold standard for assess-ing loss of muscle mass in patients with end-stage liver disease.Exercise and nutritional intervention prevail as mainstays of treatment.Compared with exercise training,nutrition interventions are targeted and tailored for patients of advanced liver disease.Therefore,this article reviewed the definition,mechanism,diagnosis and nutritional intervention of sarcopenia,in order to provide reference for nutri-tional intervention of sarcopenia in patients with end-stage liver disease.

关键词

终末期肝病/肌少症/营养干预

Key words

End-stage liver disease/Sarcopenia/Nutritional intervention

分类

医药卫生

引用本文复制引用

李智鹏,朱姝,罗秋敏,许文雄,张烨琼,郑杏容,谢婵,彭亮..终末期肝病肌少症及其营养干预研究进展[J].西南医科大学学报,2024,47(1):15-19,5.

基金项目

国家自然科学基金(82070611) (82070611)

广东省自然科学基金(2020A1515010317) (2020A1515010317)

广东省基础与应用基础研究基金(21202104030000608,2021A1515220029) (21202104030000608,2021A1515220029)

广州市科技计划项目(202102010204,2023B03J1287) (202102010204,2023B03J1287)

中山大学临床研究项目(2020007,2018009) (2020007,2018009)

中山大学科技成果转化项目(82000-18843236) (82000-18843236)

中山大学附属第三医院"五个五计划"(K00006,P02421) (K00006,P02421)

西南医科大学学报

2096-3351

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