国际眼科杂志2024，Vol.24Issue(2)：203-209,7.DOI:10.3980/j.issn.1672-5123.2024.2.05
OCT及OCTA观察垂体腺瘤患者黄斑区视网膜结构和微循环的改变
Changes of macular retinal structure and microcirculation in patients with pituitary adenoma observed by optical coherence tomography and optical coherence tomography angiography
廖智辉 1杨辛 1芦凯伦 1戴彤彤 1庞燕华2
作者信息
- 1. (524000)中国广东省湛江市,广东医科大学||(524000)中国广东省湛江市,广东医科大学附属医院眼科
- 2. (524000)中国广东省湛江市,广东医科大学附属医院眼科
- 折叠
摘要
Abstract
·AIM:To observe the changes of macular retinal structure and microcirculation in patients with pituitary adenoma(PA)by optical coherence tomography(OCT)and optical coherence tomography angiography(OCTA).
·METHODS:Cross-sectional study.A total of 40 PA patients treated at the department of neurosurgery,Affiliated Hospital of Guangdong Medical University from September 2021 to March 2023 were included as PA group,and 42 age-and gender-matched healthy volunteers were selected as normal control group.All patients underwent visual field,OCT and OCTA examinations,and the correlation of ocular parameters in PA patients was analyzed.
·RESULTS:The vessel density(VD)of each retinal layer in the macular area of the PA group was lower than that of the normal control group,and the superficial vascular complex(SVC)-VD in the macular area was positively correlated with the thickness of the macular ganglion cell complex(mGCC)(except the nasal side of the inner ring and the lower part of the outer ring;P＜0.05).The thickness of mGCC in each quadrant of the macular area and the thickness of the circumpapillary retinal nerve fiber layer(CP-RNFL)in each quadrant were negatively correlated with the mean defect(MD)value of the visual field(P＜0.05),and the area of the foveal avascular zone(FAZ)was positively correlated with the MD value(P＜0.05).
·CONCLUSION:The combination of OCT and OCTA can fully understand the microscopic changes of retinal structure and microcirculation function in PA patients,which is of great value in evaluating the preoperative visual function of PA patients.关键词
垂体腺瘤/光学相干断层扫描血管成像(OCTA)/血管密度/光学相干断层扫描(OCT)/视野/视神经Key words
pituitary adenoma/optical coherence tomography angiography(OCTA)/vessel density/optical coherence tomography(OCT)/visual field/optic nerve引用本文复制引用
廖智辉,杨辛,芦凯伦,戴彤彤,庞燕华..OCT及OCTA观察垂体腺瘤患者黄斑区视网膜结构和微循环的改变[J].国际眼科杂志,2024,24(2):203-209,7.
