国际眼科杂志2024，Vol.24Issue(2)：230-235,6.DOI:10.3980/j.issn.1672-5123.2024.2.10
青光眼中视网膜神经血管单元损伤的研究进展
Research progress of retinal neurovascular unit injury in glaucoma
欧阳灵艺 1贺涛 1邢怡桥1
作者信息
- 1. (430060)中国湖北省武汉市,武汉大学人民医院眼科中心
- 折叠
摘要
Abstract
·Glaucoma is one of the leading causes of vision loss worldwide.More and more studies have suggested that glaucoma is a complicated retinal neurovascular disease.The homeostasis imbalance of retinal neurovascular unit(RNVU)composed of neurons,glial cells and microvascular cells not only induces changes in microvascular structure and glial cells,but also affects the nerve tissue of the retina,resulting in vision loss,which there is no effective treatment to reverse,currently.Exploring the cellular composition and molecular structure of RNVU and investigating the destruction mechanism of normal cellular environment and intercellular connections in glaucoma are of great significance in exploring the pathogenesis and the treatment of glaucoma.The research progress on structural changes and dysfunction of RNVU in glaucoma are reviewed,hoping to providenew ideas for the treatment of glaucoma.关键词
青光眼/视网膜神经血管单元/视网膜神经节细胞/胶质细胞/微血管细胞Key words
glaucoma/retinal neurovascular unit/retinal ganglion cell/glial cell/microvascular cell引用本文复制引用
欧阳灵艺,贺涛,邢怡桥..青光眼中视网膜神经血管单元损伤的研究进展[J].国际眼科杂志,2024,24(2):230-235,6.
