国际眼科杂志2024，Vol.24Issue(2)：270-276,7.DOI:10.3980/j.issn.1672-5123.2024.2.18
白内障超声乳化术后视网膜微循环变化特点及影响术后视力因素分析
Characteristics of retinal microcirculation after phacoemulsification and factors affecting visual acuity
郑吉琦 1冯玉沛 1王国斌 1陈剑铭 1高琛 1张梅 1王登廷1
作者信息
- 1. (730000)中国甘肃省兰州市,甘肃省康复中心医院眼科
- 折叠
摘要
Abstract
·AIM:To investigate the changes of retinal microcirculation after phacoemulsification and the influencing factors of visual acuity.
·METHODS:Retrospective analysis.A total of 264 cataract patients(264 eyes)who underwent phacoemulsification in our hospital from January 2022 to December 2022 were selected as the study objects.Patients were divided into＜0.3 group(66 eyes)and ≥0.3 group(198 eyes)according to the recovery of best corrected visual acuity(BCVA)at 3 mo after surgery.The changes of retinal microcirculation indexes were compared before and after treatment.Logistic regression and LASSO regression models were used to screen the influencing factors of postoperative BCVA.A nomogram prediction model of postoperative BCVA was constructed and verified.A restricted cubic spline Logistic regression model was established to analyze the dose-response relationship between end-diastolic velocity(EDV),peak systolic velocity(PSV)and the risk of BCVA recovery.
·RESULTS:At 3 mo postoperatively,EDV and PSV were significantly improved compared with those before treatment,and resistance index(Rl)levels were significantly lower than those before treatment(all P＜0.05).Preoperative EDV,PSV,aqueous humor cell grade,fundus lesion grade,advanced age and Emery grade were influencing factors for poor BCVA recovery after phacoemulsification in cataract patients(P＜0.05).The AUC before and after validation of the nomogram model by Bootstrap method were 0.869(95％CI:0.815-0.903)and 0.866(95％CI:0.802-0.895),respectively.The sensitivity was 88.36％and 88.27％,and the specificity was 91.82％and 91.78％,respectively.Restricted cubic spline model analysis showed no nonlinear dose-response relationship between EDV and PSV levels and the risk of poor BCVA recovery in either male orfemale(P＞0.05).
·CONCLUSION:After phacoemulsification,retinal microcirculation in cataract patients improved significantly.EDV,PSV,aqueous humor cell grade,fundus lesion grade,advanced age and Emery grade are all factors influencing poor BCVA recovery after cataract surgery.关键词
白内障/超声乳化术/视网膜微循环/视力/影响因素Key words
cataracts/phacoemulsification/retinal microcirculation/vision/influencing factor引用本文复制引用
郑吉琦,冯玉沛,王国斌,陈剑铭,高琛,张梅,王登廷..白内障超声乳化术后视网膜微循环变化特点及影响术后视力因素分析[J].国际眼科杂志,2024,24(2):270-276,7.
