内科理论与实践2023，Vol.18Issue(5)：334-338,5.DOI:10.16138/j.1673-6087.2023.05.005
甲状旁腺全切术对维持性血液透析患者生活质量的影响
Effect of total parathyroidectomy on quality of life in maintenance hemodialysis patients
马艳 1胡梦圆 1房诗菲 1王琳1
作者信息
- 1. 大连大学附属新华医院肾内科,辽宁 大连 116021
- 折叠
摘要
Abstract
Objective To observe the effect of total parathyroidectomy(TPTX)on quality of life in maintenance hemodialysis(MHD)patients.Methods The changes of biochemical indicators including serum calcium(Ga),phosphorus(P),intact parathyroid hormone(IPTH),alkaline phosphatase(ALP),hemoglobin(Hb)and albumin(ALB)in 61 patients with secondary hyperparathyroidism(SHPT)before and after operation were retrospectively analyzed.KDQOL-36 scale and SF-36 scale were used to evaluate the quality of life of patients before and 1 year after operation.Results Postoperative symptoms such as fatigue,bone pain and skin itching were significantly improved.Postoperative serum calcium,phospho-rus,alkaline phosphatase and IPTH were significantly lower than those before operation,and hemoglobin and albumin were significantly higher than those before operation.The preoperative quality of life scores was low,while the quality of life scores were significantly increased after TPTX.Preoperative kidney disease-related quality of life,general health-relat-ed quality of life,and comprehensive quality of life were positively correlated with hemoglobin and albumin,and negative-ly correlated with age.Nephropathy-related quality of life and comprehensive quality of life were positively correlated with education level.General health-related quality of life was negatively correlated with serum urea nitrogen and phosphorus.Conclusions PTX can significantly improve the clinical indicators and the quality of life in refractory SHPT patients.关键词
继发性甲状旁腺功能亢进症/甲状旁腺全切术/生活质量/KDQOL-36/SF-36Key words
Secondary hyperparathyroidism/Total parathyroidectomy/Quality of life/Kidney disease and quality of life questionnaire/36-item short-form分类
医药卫生引用本文复制引用
马艳,胡梦圆,房诗菲,王琳..甲状旁腺全切术对维持性血液透析患者生活质量的影响[J].内科理论与实践,2023,18(5):334-338,5.
