日用化学工业（中英文）2024，Vol.54Issue(1)：80-89,10.DOI:10.3969/j.issn.2097-2806.2024.01.011
祛斑美白类化妆品功效成分的研究现状
Advances of functional components in whitening cosmetic
摘要
Abstract
Excessive accumulation of melanin pigments may result in skin-related disorders such as post inflammatory pigmentation,solar lentigo,melasma and freckles.The mechanism of action of whitening cosmetics is related to the inhibition of melanin synthesis,reduction of me lanin,a nd inhibition of melanosome transport.The whitening raw materials in spot-removing and whitening cosmetics achieve whitening effects by inhibiting the rate-limiting enzyme tyrosinase of the melanin biosynthesis pathway,participating in the regulation of the melanin biosynthesis signaling pathway,and reducing melanin or inhibiting melanosome transport and other mechanisms of action.With the increasing market demand for spot-removing and whitening cosmetics,more and more natural active ingredients are added to the cosmetics as whitening raw materials,but there are problems such as unclear composition and missing mechanism of action.In sequence to provide a theoretical foundation for the clinical strategy of skin pigmentation prevention and treatment as well as the product development of whitening cosmetics,the action mechanisms of the existing whitening cosmetic efficacy components cosmetics are sorted out and discussed in this paper.关键词
黑色素/祛斑美白类化妆品/酪氨酸酶Key words
melanin/whitening cosmetics/tyrosinase分类
化学化工引用本文复制引用
李宁,李恩念,陈红波,程芳,邹衡芳,陈鸿鹏..祛斑美白类化妆品功效成分的研究现状[J].日用化学工业（中英文）,2024,54(1):80-89,10.基金项目
广东省农村科技特派员项目(KTP20200175) （KTP20200175）
云浮市乡村振兴与科技创新项目(2022020407) （2022020407）
