日用化学品科学2024，Vol.47Issue(1)：16-21,6.DOI:10.3969/j.issn.1006-7264.2024.01.004
指橙活性物的提取方法及其功效评价
Extraction and evaluation of actives in finger lime
蔡晓桐 1袁菊懋 1马洁1
作者信息
- 1. 上海科黛生物科技有限公司,上海 201703
- 折叠
摘要
Abstract
Ultraviolet photocatalysis was used to extract active substances from finger lime,in which the method was environmentally friendly and easy to be operated.The results of physical and chemical test showed that the content of citric acid and the content of malic acid in finger lime extract were 35.2 mg/mL and 2.7 mg/mL,respectively.As shown in the safety tests including chicken embryo chorioallantoic membrane(CAM)and in vitro human epidermal model,2%(v/v)finger lime extract was safe and non-irritating.As measured with the methods of bicinchoninic acid(BCA)and cytometry,the number of exfoliated keratinocytes and the protein content were both increased,indicative of the exfoliating effect of the extract.As to anti-inflammatory tests,the sample group inhibited the expression of TNF-α,IL-6 and IL-8 dramatically,indicating that the sample had soothing and repairing effects.关键词
苹果酸/柠檬酸/安全性/角质形成细胞/修复Key words
malic acid/citric acid/safety/keratinocyte/repairing分类
化学化工引用本文复制引用
蔡晓桐,袁菊懋,马洁..指橙活性物的提取方法及其功效评价[J].日用化学品科学,2024,47(1):16-21,6.
