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经口达芬奇机器人甲状腺乳头状癌手术100例临床分析OACSTPCD

Transoral Robotic Thyroidectomy for Papillary Thyroid Carcinoma:Clinical Analysis of 100 Cases

中文摘要英文摘要

目的:探讨经口前庭入路机器人甲状腺切除术(transoral robotic thyroidectomy vestibular approach,TORT-VA)在甲状腺乳头状癌(papillary thyroid carcinoma,PTC)患者中的临床应用及可行性.方法:回顾性收集 2018年 12 月至 2022 年 2 月在大坪医院乳腺甲状腺外科接受TORTVA的PTC患者 100 例,回顾性分析其手术方式、手术时间、术后并发症、住院时间及甲状旁腺素、血清钙水平等临床资料.结果:100 例患者中,女性 86 例,男性 14例;平均年龄(38.30±10.30)岁,平均肿瘤长径(0.91±0.51)cm.行单侧甲状腺腺叶及峡部切除加中央区淋巴结清扫 77 例,甲状腺全切加单侧中央区淋巴结清扫 7 例,甲状腺全切加双侧中央区淋巴结清扫 16 例.平均手术时间(235.00±51.50)min.清扫淋巴结中位数 7(4,11)枚.清扫转移淋巴结中位数 1(0,2)枚.术后平均住院时间(2.39±0.90)d.术后出现暂时性喉返神经损伤导致的声音嘶哑2例,颏神经暂时性麻痹导致的下颌麻木7例,暂时性甲状旁腺功能减退症 8 例.2 例患者分别因术中出血和暴露困难致使中转开放手术,余 98 例均顺利完成TORT-VA.患者中位随访时间 25 个月(16.30~54.10 个月),随访期间均未出现肿瘤复发或转移.结论:通过严格把握手术适应证,由具有经验的术者对PTC患者实施TORTVA是安全可行的,可以为患者提供更多的选择.

Objective:To explore the clinical application and practicability of the transoral robotic thyroidectomy vestibular ap-proach(TORTVA)in papillary thyroid carcinoma(PTC)patients.Methods:A total of 100 PTC patients who underwent TORTVA at the department of breast and thyroid surgery in Daping Hospital from December 2018 to February 2022 were collected in our research.The clinical features including operation approaches,operation time,postoperative complications,length of stay and laboratory indexes such as parathyroid hormone and serum calcium levels were retrospectively analyzed.Results:Among the 100 patients,86 were women and 14 were men.The average age was(38.30±10.30)years,and the average tumor size was(0.91±0.51)cm.Among these 100 patients,77 patients underwent unilateral lobectomy plus isthmus resection and central neck dis-section,7 patients underwent total thyroidectomy and unilateral central neck dissection,and 16 patients underwent total thyroid-ectomy and bilateral central neck dissection.The average operation time was(235.00±51.50)minutes.The median number of lymph nodes dissected was 7(4,11),and the median number of metastatic lymph nodes dissected was 1(0,2),The average postoperative length of stay was(2.39±0.90)days.After operation,vocal cord palsy caused by temporary recurrent laryngeal nerve injury occurred in 2 pa-tients,and temporary mental nerve paralysis occurred in 7 patients,and transient hypoparathyroidism was found in 8 patients.2 patients were transferred to open surgery due to intraoperative bleeding and exposure difficulties,and TORTVA was successfully completed in the other 98 patients.The median follow-up time of the patients was 25(16.30,54.10)months,and neither recurrence nor metastasis was observed during the follow-up period.Conclusion:TORTVA performed with strict surgical indications and by experienced operators is safe and feasible for PTC patients,and can provide more choices for patients.

徐静;张姝;姜燕;张哲;徐琰

400042 重庆,中国人民解放军陆军军医大学 大坪医院 乳腺甲状腺外科

临床医学

经口前庭入路达芬奇机器人甲状腺切除术甲状腺乳头状癌

Oral vestibular approachDa Vinci robotsThyroidectomyPapillary thyroid carcinoma

《肿瘤预防与治疗》 2024 (001)

52-61 / 10

This study was supported by grants from Chongqing Science and Technology Bureau(No.CSTC2019jscx-msx-mX0196)and Chongqing Municipal Education Commission(No.yjg193129). 重庆市技术创新与应用发展专项面上项目(编号:CSTC2019jscx-msxmX0196);重庆市研究生教育教学改革研究项目(编号:yjg193129)

10.3969/j.issn.1674-0904.2024.01.007

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