摘要
Abstract
Objective:To observe the effect of Qiwei Baizhu Powder combined with Buyang Huanwu Decoction on glucose and lipid metabolism and insulin resistance in patients with obesity and type 2 diabetes mellitus(T2DM).Methods:A total of 86 patients with obesity and T2DM who were admitted to the hospital from January 2020 to October 2022 were selected,and divided into the study group(n=43)and the control group(n=43)by random number table method.The control group was given con-ventional treatments,while the study group was treated with Qiwei Baizhu Powder combined with Buyang Huanwu Decoction on this basis.Clinical effects,TCM syndrome scores,glucose and lipid metabolism indicators and insulin resistance were compared between the two groups.Results:After treatment,the total clinical response rate in the study group(90.70％)was higher than that in the control group(74.42％)(P＜0.05).TCM syndrome scores were lower than those in the control group(P＜0.05).The levels of 2h postprandial blood glucose(P2hPG),glycated hemoglobin(HbA 1 c),triglyceride(TG),total cholesterol(TC),low-density lipoprotein(LDL),body mass index(BMI),fasting insulin(FINS)and insulin resistance index(HOMA-IR)in both groups decreased.These indicators in the study group were lower than those in the control group(P＜0.05).The lev-els of high density lipoprotein(HDL)increased,and the level in study group was higher than that in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion:Qiwei Baizhu Powder combined with Buyang Huanwu Decoction is effective in the treatment of patients with obesity and T2DM,which can effectively improve glucose and lipid metabolism,thereby alleviating insulin resistance.关键词
七味白术散/补阳还五汤/肥胖症/2型糖尿病/糖脂代谢/胰岛素抵抗Key words
Qiwei Baizhu Powder/Buyang Huanwu Decoction/Obesity/Type 2 diabetes mellitus/Glucose and lipid me-tabolism/Insulin resistance分类
医药卫生
