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非编码RNA对胰腺癌发生进展及耐药的影响

吴念平 周策凡 唐景峰

生命科学研究2023,Vol.27Issue(6):488-497,10.
生命科学研究2023,Vol.27Issue(6):488-497,10.DOI:10.16605/j.cnki.1007-7847.2022.11.0230

非编码RNA对胰腺癌发生进展及耐药的影响

Effects of Non-coding RNAs on Occurrence,Progression and Drug Resistance of Pancreatic Cancer

吴念平 1周策凡 1唐景峰1

作者信息

  • 1. 湖北工业大学 科技部/教育部细胞调控与分子药物学科"111"引智基地发酵工程教育部重点实验室工业发酵省部共建协同创新中心工业微生物湖北省重点实验室,中国 湖北 武汉 430068
  • 折叠

摘要

Abstract

Non-coding RNAs(ncRNAs),which are abundant in organisms,have been of special concern in recent years.Most ncRNAs do not encode proteins,but they play a significant role in participating complex signaling cascades in various diseases by regulating gene expression and protein functions.Pancreatic cancer is known as the king of cancer because its early symptoms are not obvious,diagnosis often occurs at an ad-vanced stage of the disease and its treatment effect and prognosis are extremely poor.There is still a long way to go in scientific research of pancreatic cancer.This article describes the mechanism of ncRNAs in the occurrence,progression and drug resistance of pancreatic cancer,hoping to provide some ideas for re-searchers to find targets for the tumor detection and treatment.

关键词

非编码RNA(ncRNA)/胰腺癌/耐药

Key words

non-coding RNA(ncRNA)/pancreatic cancer/drug resistance

分类

生物科学

引用本文复制引用

吴念平,周策凡,唐景峰..非编码RNA对胰腺癌发生进展及耐药的影响[J].生命科学研究,2023,27(6):488-497,10.

基金项目

国家自然科学基金面上项目(31871176,32070726) (31871176,32070726)

生命科学研究

OACSTPCD

1007-7847

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