快速样品前处理技术-超高效液相色谱串联质谱法测定粮谷中7种真菌毒素OACSTPCD

QuEChER,a fast and fast sample preprocessing technology(quick、easy、cheap、effective、rugged、safe),was applied to determine the contents of seven mycotoxin residues in grains through the combination with UPLC-MS/MS.After the samples were extracted with acetonitrile-water-formic acid(84:15.5:0.5)solution and purified by N-propyl ethylene diamine(PSA),UPLC-MS/MS was used for the detection.The excellent linearity was observed for the seven mycotoxins in the concentration range of 0.15-250 μg/L,with the correlation coefficients(R2)higher than 0.99.In addition,the detection and quantification limits of our method were 0.02-13.22 μg/L and 0.08-39.55 μg/L,respectively.The average spiked recoveries were 82.44％-103.12％,with RSD less than 10％.When this method was utilized to measure the seven mycotoxins in rice,beans,peanuts and other cereal crops,the spiked recoveries turned out to be greater than 82％,further demonstrating the general applicability of our analytical method.