护理研究2024，Vol.38Issue(2)：267-272,6.DOI:10.12102/j.issn.1009-6493.2024.02.012
年轻老年帕金森病病人认知障碍的影响因素及其预测模型构建
Influencing factors and prediction model construction of cognitive impairment in young-old patients with Parkinson's disease
摘要
Abstract
Objective:To investigate the risk factors for cognitive impairment in the young-old patients with Parkinson's disease(PD),and to construct a prediction model based on the risk factors.Methods:A total of 164 young-old PD patients who completed the 5-year follow-up from PPMI database were included in this study.Montreal Cognitive Assessment(MoCA)was used to assess cognitive function.164 young-old PD patients were divided into cognitive normal group(PD-NC)and cognitive impairment group(PD-CI).Logistic regression analysis was used to explore the risk factors for cognitive impairment in young-old patients with PD,and a predictive model was constructed based on these factors.Results:Among 164 young-old PD patients,101 were in the PD-NC group and 63 were in the PD-CI group,and the incidence of cognitive impairment was 38.4%.Logistic regression analysis showed that age,years of education,MDS-UPDRSⅡand MDS-UPDRS Ⅲ scores entered the regression equation.The AUC of the constructed prediction model was 0.815.Conclusions:The cognitive function of young-old patients with PD is affected by age,years of education,activities of daily living and motor function.The established prediction model has good discrimination and calibration,which can provide a reference for early screening and intervention of cognitive impairment in young-old patients with PD.关键词
帕金森病/年轻老年人/认知障碍/影响因素/日常生活活动能力/运动功能/预测模型/护理Key words
Parkinson's disease/the young-old/cognitive impairment/influencing factors/activities of daily living,ADL/motor function/prediction model/nursing care引用本文复制引用
崔晓芳,路筱,余红梅,韩红娟..年轻老年帕金森病病人认知障碍的影响因素及其预测模型构建[J].护理研究,2024,38(2):267-272,6.基金项目
国家自然科学基金项目,编号:82273742 （）
