实用医学杂志2024，Vol.40Issue(1)：114-118,5.DOI:10.3969/j.issn.1006-5725.2024.01.020
补肾化瘀强骨方对肾虚血瘀型老年骨质疏松性腰椎骨折的疗效
Effects of Busheng Huayu Qianggu prescription in elderly patients with osteoporotic lumbar fracture of kidney deficiency and blood stasis type
摘要
Abstract
Objective To investigate the application value of Bushen Huayu Qianggu prescription in the treatment of senile osteoporotic lumbar fracture with kidney deficiency and blood stasis type.Methods All elderly patients with osteoporotic lumbar fractures of kidney deficiency and blood stasis were treated in our hospital from September 2021 to March 2023 and randomly divided into 68 cases in both groups.The control group was treated with conventional Western medicine,and the observation group was treated with BushengHuayuQiang Gu prescrip-tion for 12 weeks.Results Serum D-dimer(D-D),interleukin-6(IL-6)and prostaglandin E2(PGE2)were lower in the observation group than in the control group,and vascular endothelial growth factor(VEGF)and β-endorphin(β-EP)were higher(P<0.05);serum osteoprotegerin(OPG)and bone morphogenetic protein-2(BMP-2)were higher in the observation group(P<0.05);total effective rate was as high as 95.59%(65%)(P<0.05);bone mineral density(BMD)was higher in the observation group than in the control group after treatment,and the total symptom score and Cobb angle of Chinese medicine were lower(P<0.05);the total effective rate of the observation group was as high as 95.59%(65/68),higher than that of the control groupwhich was 80.88%(55/68)(P<0.05).Conclusion Combined treatment with BushenHuayuQianggu prescription can reduce inflammation,regulate bone metabolism,promote bone mineral density and improve clinical efficacy for senily-aged lumbar osteoporotic frac-ture caused by kidney deficiency and blood stasis.关键词
补肾化瘀强骨方/肾虚血瘀型/骨质疏松性腰椎骨折Key words
Bushen Huayu Qianggu prescription/kidney deficiency and blood stasis type/osteopo-rotic lumbar fracture分类
医药卫生引用本文复制引用
邱国栋,孙雷,谢水华..补肾化瘀强骨方对肾虚血瘀型老年骨质疏松性腰椎骨折的疗效[J].实用医学杂志,2024,40(1):114-118,5.基金项目
江西省中医药管理局科技计划项目(编号:2022B839) （编号:2022B839）
