实用医学杂志2024，Vol.40Issue(1)：119-122,128,5.DOI:10.3969/j.issn.1006-5725.2024.01.021
宏基因二代测序在脊柱感染诊治中的应用进展
Application of metagenomics next-generation sequencing in the diagnosis and treatment of spinal infection
摘要
Abstract
The incidence of spinal infections,a relatively rare infectious disease,is on the rise due to the empirical use of antibiotics that increases the chances of infection with drug-resistant bacteria,as well as advances in testing technology that have led to an increase in detection rates.Identifying the type of pathogen to target antibi-otics is the key to treatment.However,conventionaldetection methods have low detection rates and are time-consum-ing,which are not conducive to the rapid and accurate diagnosis of spinal infection.Metagenomics next-generation sequencing(mNGS)is a detection technique that can sequence all nucleic acid fragments in samples,the emer-gence of which subverts traditional detection methods and plays an important role in the diagnosis and treatment of spinal infections.This article summarizes the application of mNGS in the diagnosis and treatment of spinal infection.关键词
宏基因二代测序/脊柱感染/病原体/临床用药Key words
metagenomics next-generation sequencing/spinal infection/pathogens/clinical medication分类
医药卫生引用本文复制引用
龙思萍,刘志礼,黄山虎,刘家明..宏基因二代测序在脊柱感染诊治中的应用进展[J].实用医学杂志,2024,40(1):119-122,128,5.基金项目
江西省"双千计划"首批培养类项目 （）
中央引导地方科技发展资金(编号:20222ZDH04095) （编号:20222ZDH04095）
江西省重点研发计划项目(编号:20223BBG71S02) （编号:20223BBG71S02）
